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Platelet TLR4 at the crossroads of thrombosis and the innate immune response
(Federation of American Societies for Experimental Biology, 2018-12-04)
Platelet TLR-4 activation by pathogen- or damage-associated molecular pattern molecules triggers pro-thrombotic, proinflammatory, and pro-coagulant effector responses. Moreover, platelet TLR4 has a prominent role as a ...
SÍNDROME DE MAY-THURNER
(Universidad de Costa Rica, 2019)
Platelet function in patients with lupus anticoagulant and thrombosis
(Universidad del Zulia, 2013)
A high-risk laboratory profile of antiphospholipid antibodies and thrombosis is associated with a large number of extra-criteria manifestations in obstetric antiphospholipid syndrome
(Humana Press, 2019-12)
Extra-criteria manifestations such as thrombocytopenia and livedo are described associated with antiphospholipid syndrome (APS) but are not included in the current classification criteria. Their clinical expression might ...
Von Willebrand factor (VWF) as a risk factor for bleeding and thrombosis
(Maney Publishing, 2012-04)
The von Willebrand factor (VWF) is analysed as a bleeding and thrombotic risk marker. When the VWF level is increased, it predicts a thrombotic phenotype and when VWF level is low in plasma, the phenotype varies to bleeding ...
Platelets as mediators of Thromboinflammation in chronic Myeloproliferative Neoplasms
(Frontiers Research Foundation, 2019-06-14)
Chronic myeloproliferative neoplasms (MPN) are stem cell disorders driven by mutations in JAK2, CALR, or MPL genes and characterized by myeloid proliferation and increased blood cell counts. They encompass three closely ...
Morbidity of lupus anticoagulants in children: A single institution experience
(Pergamon-Elsevier Science Ltd, 2004-01)
Introduction: The lupus anticoagulant (LA) and the anticardiolipin antibodies (ACA) are the antiphospholipid antibodies more relevant clinically. Their clinical manifestations are diverse with most patients being asymptomatic ...
Caudal vena cava thrombosis in a dairy cow (Bos taurus) in Argentina
(2017)
Caudal vena cava thrombosis (CVCT) is an acute disease secondary to ruminal lactic acidosis and rumenitis with fatal outcome in cattle fed with a high-grain diet. The aim of this paper is to describe CVCT in an adult ...
Platelet toll-like receptors in thromboinflammation
(Frontiers in Bioscience, 2017-06)
Besides their undiscussed role in hemostasis and thrombosis, platelets are also key effector cells capable of assisting and modulating inflammatory reactions and immune responses. Platelets play a sentinel role in immune ...
A focus on the roles of histones in health and diseases
(Pergamon-Elsevier Science Ltd, 2021-08)
Over time, the knowledge on the role of histones has significantly changed. Initially, histones were only known as DNA packaging proteins but later, it was discovered that they act extracellularly as powerful antimicrobial ...