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Photodynamic inactivation to prevent and disrupt Staphylococcus aureus biofilm under different media conditions
(Wiley Blackwell Publishing, Inc, 2019-09)
Objective: The goal of this work was to investigate the photodynamic activity of 5,10,15,20-tetrakis[4-(3-N,N-dimethylaminopropoxy)phenyl]chlorin (TAPC) and zinc(II) 2,9,16,23-tetrakis[4-(N-methylpyridyloxy)]phthalocyanine ...
Photodynamic inactivation of multiresistant bacteria (KPC) using zinc(II)phthalocyanines
(Elsevier, 2017-09)
The worldwide increase in antibiotic resistance has led to search of alternatives anti-microbial therapies such as photodynamic inactivation. The aim of this paper was to evaluate the photodynamic activity in vitro of a ...
Poly(propylene)-based Films Modified with a Tetracationic Phthalocyanine with Applications in Photodynamic Inactivation of Candida albicans
(Taylor, 2018-02)
Photoactive films based on polymer-like poly(propylene) were generated and utilized as support of zinc(II)tetramethyltetrapyridino[2,3-b:2′,3′-g:2″,3″-l:2″′,3″′-q]porphyrazinium salt (ZnTM2,3PyPz). Using a photograft ...
Synthesis and photodynamic properties of amphiphilic A3B- phthalocyanine derivatives bearing N-heterocycles as potential cationic phototherapeutic agents
(Elsevier, 2011-10)
Unsymmetrically substituted A3B-phthalocyanine derivatives bearing annulated 6-membered N-heterocycles, pyridine and pyrazine rings, were synthesized by the ring expansion reaction of boron(III) subphthalocyanine chloride. ...
Mechanistic insight of the photodynamic inactivation of Escherichia coli by a tetracationic zinc(II) phthalocyanine derivative
(Elsevier Science, 2009-03)
Photodynamic inactivation (PDI) of Escherichia coli has been studied in cultures treated with zinc(II) 2,9,16,23-tetrakis[4-(N-methylpyridyloxy)]phthalocyanine (ZnPPc+4) to obtain insight about the mechanism of damage. ...
Enhancement of photodynamic inactivation of Staphylococcus aureus biofilms by disruptive strategies
(Springer London Ltd, 2017-11)
Photodynamic inactivation (PDI) has been used to inactivate microorganisms through the use of photosensitizers and visible light. On the one hand, near-infrared treatment (NIRT) has also bactericidal and dispersal effects ...
Phenotypic resistance in photodynamic inactivation unravelled at the single bacterium level
(American Chemical Society, 2019-07-09)
Herein we report a simple fluorescence microscopy methodology that, jointly with four photosensitizers (PSs) and a cell viability marker, allows monitoring of phenotypic bacterial resistance to photodynamic inactivation ...
Mechanistic studies of Candida albicans photodynamic inactivation with Porophyllum obscurum hexanic extract and its isolated thiophenic compounds
(Elsevier Science, 2019-06)
Porophyllum obscurum (Spreng) DC (Asteraceae) hexanic extract (PoHex) from aerial parts has demonstrated antifungal activity under UVA irradiation against Candida spp. isolates from patients with oropharyngeal candidiasis ...
ROS-generating rare-earth coordination networks for photodynamic inactivation of Candida albicans
(Royal Society of Chemistry, 2021-03-31)
Water–ethanol suspensions of 2D coordination network (CN) based on rare earth elements and mixed ligands were evaluated as reactive oxygen species (ROS) generators under UV light irradiation, in contact with a biomimetic ...
Photodynamic inactivation of ESKAPE group bacterial pathogens in planktonic and biofilm cultures using metallated porphyrin-doped conjugated polymer nanoparticles
(American Chemical Society Inc, 2020-06)
Photodynamic inactivation (PDI) protocols using photoactive metallated porphyrin-doped conjugated polymer nanoparticles (CPNs) and blue light were developed to eliminate multidrug-resistant pathogens. CPNs-PDI protocols ...