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Neisseria gonorrhoeae Induces a Tolerogenic Phenotype in Macrophages to Modulate Host Immunity
(Hindawi, 2013)
Neisseria gonorrhoeae is the etiological agent of gonorrhoea, which is a sexually transmitted disease widespread throughout the
world. N. gonorrhoeae does not improve immune response in patients with reinfection, suggesting ...
A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines
(BioMed Central, 2013)
Background: Generation of tolerogenic dendritic cells (TolDCs) for therapy is challenging due to its implications for
the design of protocols suitable for clinical applications, which means not only using safe products, ...
Role of dendritic cells in the induction of lymphocyte tolerance
(Frontiers Media, 2015)
The ability of dendritic cells (DCs) to trigger tolerance or immunity is dictated by the context in which an antigen is encountered. A large body of evidence indicates that antigen presentation by steady-state DCs induces ...
Vitamin D-3 Induces IDO+ Tolerogenic DCs and Enhances Treg, Reducing the Severity of EAE
(Wiley-blackwellHobokenEUA, 2013)
Progesterone and VIP cross-talk enhances phagocytosis and anti-inflammatory profile in trophoblast-derived cells
(Elsevier Ireland, 2017-03)
Trophoblast cells produce several inmmuneregulators like the Vasoactive Intestinal Peptide (VIP) and P4 targeting multiple circuits, and also display an intese phagocytic ability allowing embryo implantation in a tolerogenic ...
Allogeneic apoptotic thymocyte-stimulated dendritic cells expand functional regulatory T cells
(WILEY-BLACKWELL, 2011)
P>Dendritic cells (DCs) play an important role in the clearance of apoptotic cells. The removal of apoptotic cells leads to peripheral tolerance, although their role is still not clear. We show that the uptake of apoptotic ...
Hormonal Modulation of Dendritic Cells Differentiation, Maturation and Function: Implications for the Initiation and Progress of Systemic Autoimmunity
(Birkhauser Verlag Ag, 2017-04)
Hormonal homeostasis is crucial for keeping a competent and healthy immune function. Several hormones can modulate the function of various immune cells such as dendritic cells (DCs) by influencing the initiation of the ...
Benzalkonium chloride breaks down conjunctival immunological tolerance in a murine model
(Nature Publishing Group, 2012-06)
The impact of topical eye drops with benzalkonium chloride (BAK) as a preservative could involve more than the reported toxic effects on the ocular surface epithelium and ultimately affect the immune balance of the ...
Contribution of Vasoactive Intestinal Peptide to Immune Homeostasis in Trophoblast-Maternal Leukocyte Interaction under LPS Stimulation
(Karger, 2013-12)
Background/Aims: The maternal-fetal interface is a unique immunological site that generates an adequate microenvironment during pregnancy, recognizing and eliminating infections and tolerating the trophoblast/placenta unit. ...