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The insular cortex modulates cardiovascular responses to acute restraint stress in rats
(ELSEVIER SCIENCE BV, 2010)
Acute restraint is an unavoidable stress situation that evokes marked and sustained cardiovascular changes, which are characterized by blood pressure and heart rate increases. In the present study, we tested the hypothesis ...
Neuroanatomical basis of behavioral disturbances in patients with prefrontal lesions
(Sociedad de Biología de Chile, 2006)
DIFFERENT ROLE OF THE VENTRAL MEDIAL PREFRONTAL CORTEX ON MODULATION OF INNATE AND ASSOCIATIVE LEARNED FEAR
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Reversible inactivation of the ventral portion of medial prefrontal cortex (vMPFC) of the rat brain has been shown to induce anxiolytic-like effects in animal models based on associative learning. The role of this brain ...
Muscarinic acetylcholine neurotransmission enhances the late-phase of long-term potentiation in the hippocampal-prefrontal cortex pathway of rats in vivo: A possible involvement of monoaminergic systems
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
The prefrontal cortex is continuously required for working memory processing during wakefulness, but is particularly hypoactivated during sleep and in psychiatric disorders such as schizophrenia. Ammon`s horn CA1 hippocampus ...
Interaction of dopamine D1 with NMDA NR1 receptors in rat prefrontal cortex
(Elsevier, 2009-01)
Despite the tremendous importance of D1 and NMDA receptors to cognition (working memory, executive functions) and synaptic plasticity in the prefrontal cortex (PFC), little is known about the molecular mechanisms underlying ...
Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
Schizophrenia is likely to be a consequence of serial alterations in a number of genes that, together with environmental factors, will lead to the establishment of the illness. The dorsolateral prefrontal cortex (Brodmann`s ...
Protein malnutrition during gestation and early life decreases neuronal size in the medial prefrontal cortex of post-pubertal rats
(Elsevier B.V., 2017-12-01)
Retrospective studies in human populations indicate that protein deprivation during pregnancy and early life (early protein malnutrition, EPM) is associated with cognitive impairments, learning disabilities and may represent ...
Differential effect of environment enrichment and social isolation on depressive-like behavior, spontaneous activity and serotonin and norepinephrine concentration in prefrontal cortex and ventral striatum
(2008)
Dawley rats were reared from weaning in either social isolation, standard laboratory conditions, or environmental enrichment. Open-field activity
was assessed at postnatal days 37, 65, 93 and 107 and 1 h before the last ...
Serotonin 2a Receptor and Serotonin 1a Receptor Interact Within the Medial Prefrontal Cortex During Recognition Memory in Mice
(Frontiers Research Foundation, 2015-12)
Episodic memory, can be defined as the memory for unique events. The serotonergic system one of the main neuromodulatory systems in the brain appears to play a role in it. The serotonin 2a receptor (5-HT2aR) one of the ...
Refinement of neuronal synchronization with gamma oscillations in the medial prefrontal cortex after adolescence
(Public Library of Science, 2013-04)
The marked anatomical and functional changes taking place in the medial prefrontal cortex (PFC) during adolescence set grounds for the high incidence of neuropsychiatric disorders with adolescent onset. Although circuit ...