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The compound 14-keto stypodiol diacetate from the algae Stypopodium flabelliforme inhibits microtubules and cell proliferation in DU-145 human prostatic cells
(1998)
We investigated the effects of the drug 14-keto-stypodiol diacetate (SDA) extracted from the seaweed product Stypopodium flabelliforme, in inhibiting the cell growth and tumor invasive behavior of DU-145 human prostate ...
Tubulin, actin, and tau protein interactions and the study of their macromolecular assemblies
(2002)
The intracellular polymerization of cytoskeletal proteins into their supramolecular assemblies raises many questions regarding the regulatory patterns that control this process. Binding experiments using the ELISA solid ...
Marlin-1 is expressed in testis and associates to the cytoskeleton and GABAB receptors
(2008)
Marlin-1 is a GABAB receptor and Jak tyrosine kinase-binding protein that also associates with RNA and microtubules. In humans and rodents, expression of Marlin-1 is predominantly restricted to the brain, but expression ...
A gathering of neuronal cytoskeletal scientists in South America
(2012)
This essay attempts to capture the spirit of our recent meeting in Chile entitled "Emerging Concepts in Neuronal Cytoskeleton." The purpose of the meeting was to bring together scientists from South American countries with ...
MAP1B Regulates Axonal Development by Modulating Rho-GTPase Rac1 Activity
(AMER SOC CELL BIOLOGY, 2010-08-09)
Cultured neurons obtained from MAP1B-deficient mice have a delay in axon outgrowth and a reduced rate of axonal
elongation compared with neurons from wild-type mice. Here we show that MAP1B deficiency results in a ...
Tubulin polyglutamylation is a general traffic-control mechanism in hippocampal neurons
(Company of Biologists, 2020)
Neurons are highly complex cells that heavily rely on intracellular transport to distribute a range of functionally essential cargoes within the cell. Post-translational modifications of tubulin are emerging as mechanisms ...
Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1
(PORTLAND PRESS LTD, 2005-07-15)
For neuronal migration to occur, the cell must undergo morphological changes that require modifications of the cytoskeleton. Several different MAPs (microtubule-associated proteins) or actin-binding proteins are proposed ...
Purification and characterization of the high molecular weight microtubule associated proteins from neonatal rat brain
(Kluwer Academic Publishers, 1994)
The changes in the levels of microtubule-associated proteins (MAPs) during advanced embryonic stages, neonatal and adult organisms reflect the importance of these cytoskeletal proteins in relation to the morphogenesis of ...
Microtubule-Associated Protein 1B Function during Normal Development, Regeneration, and Pathological Conditions in the Nervous System
(Wiley Periodicals, Inc., 2004)
Microtubule-associated protein 1B is
the first MAP to be expressed during the development of
the nervous system. Several different approaches have
revealed that MAP1B function is associated with microtubule
and actin ...
The compound 14-keto-stypodiol diacetate from the algae Stypopodium flabelliforme inhibits microtubules and cell proliferation in DU-145 human prostatic cells
(1998)
We investigated the effects of the drug 14-keto-stypodiol diacetate (SDA) extracted from the seaweed product Stypopodium
flabelliforme, in inhibiting the cell growth and tumor invasive behavior of DU-145 human prostate ...