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Membrane fluidization by alcohols inhibits DesK-DesR signalling in Bacillus subtilis
(Elsevier Science, 2018-03)
After cold shock, the Bacillus subtilis desaturase Des introduces double bonds into the fatty acids of existing membrane phospholipids. The synthesis of Des is regulated exclusively by the two-component system DesK/DesR; ...
Development of charged ion exchange resin-polymer ultrafiltration membranes to reduce organic fouling
(Elsevier Science, 2006-07-05)
This work deals with the performance of polymeric membranes charged with an ion exchange resin on the ultrafiltration (UF) of an oily suspension. The membranes were prepared by the phase inversion process from polysulfone ...
L-ascorbic acid alkyl esters action on stratum corneum model membranes: an insight into the mechanism for enhanced skin permeation
(Elsevier Science, 2019-11)
L-ascorbic acid alkyl esters (ASCn) are lipophilic forms of vitamin C, which act as skin permeation enhancers. We investigated the physical changes induced by incorporating ASCn into stratum corneum (SC) lipid membranes ...
Cholesterol and desmosterol incorporation into ram sperm membrane before cryopreservation: Effects on membrane biophysical properties and sperm quality
(Elsevier Science, 2020-09-01)
Ram sperm are particularly sensitive to freeze-thawing mainly due to their lipid composition, limiting their use in artificial insemination programs. We evaluated the extent of cholesterol and desmosterol incorporation ...
Hopanoids, like sterols, modulate dynamics, compaction, phase segregation and permeability of membranes
(Elsevier Science, 2019-12)
In recent years, hopanoids, a group of pentacyclic compounds found in bacterial membranes, are in the spotlight since it was proposed that they induce order in lipid membranes in a similar way cholesterol do in eukaryotes, ...
Membrane-based processes: Optimization of hydrogen separation by minimization of power, membrane area, and cost
(MDPI, 2018-11)
This work deals with the optimization of two-stage membrane systems for H2 separation from off-gases in hydrocarbons processing plants to simultaneously attain high values of both H2 recovery and H2 product purity. First, ...
Miltefosine inhibits the membrane remodeling caused by phospholipase action by changing membrane physical properties
(Elsevier Science, 2020-10)
Miltefosine (hexadecylphosphocholine or HePC) is an alkylphosphocholine approved for the treatment of visceral and cutaneous Leishmaniasis. HePC exerts its effect by interacting with lipid membranes and affecting ...
Relevance of the protein macrodipole in the membrane-binding process. Interactions of fatty-acid binding proteins with cationic lipid membranes
(Public Library of Science, 2018-03)
The fatty acid-binding proteins L-BABP and Rep1-NCXSQ bind to anionic lipid membranes by electrostatic interactions. According to Molecular Dynamics (MD) simulations, the interaction of the protein macrodipole with the ...
Interaction of the small-molecule kinase inhibitors tofacitinib and lapatinib with membranes
(Elsevier Science, 2020-11)
Lapatinib and tofacitinib are small-molecule kinase inhibitors approved for the treatment of advanced or metastatic breast cancer and rheumatoid arthritis, respectively. So far, the mechanisms which are responsible for ...