Buscar
Mostrando ítems 1-10 de 1862
Generation of T. cruzi-Specific Primary CD4+ T Cell Lines from Peripheral Blood Mononuclear Cells Isolated from Chagas Disease Patients
(Springer, 2019)
Human CD8+ and CD4+ T cell lines and clones are valuable tools to explore the role of these cells in the context of diseases, especially in cases in which the main underlying actor is the immune response, like Chagas ...
Pulsing Dendritic Cells with Whole Tumor Cell Lysates
(Springer, 2014-03)
One of the strategies employed in immunotherapy for cancer is to use of ex vivo-generated dendritic cells (DC) pulsed with tumor antigens. Several approaches have been used to obtain and load tumor antigens in DC. One such ...
Evaluation of apoptosis markers in different cell lines infected with equine arteritis virus
(Informa Healthcare, 2019-02-23)
Equine arteritis virus (EAV) induces apoptosis in infected cells. Cell death caused by EAV has been studied mainly using three cell lines, BHK-21, RK-13 and Vero cells. The mechanism of apoptosis varies among cell lines ...
Additive apoptotic effect of STI571 with the cytoprotective agent amifostine in K-562 cell line
(Springer, 2005-06)
Purpose: To study the apoptotic effect of the 2-phenylaminopyrimidine derivative STI571 in combination with antioxidant agents on K-562 cell line derived from a Philadelphia chromosome-positive chronic myeloid leukemia ...
Establishment and characterization of a Madin-Darby canine kidney reporter cell line for influenza A virus assays
(American Society for Microbiology, 2010-07)
Influenza virus diagnosis has traditionally relied on virus isolation in chicken embryo or cell cultures. Many laboratories have adopted rapid molecular methods for detection of influenza viruses and discontinued routine ...
Chlorpyrifos inhibits cell proliferation through ERK1/2 phosphorylation in breast cancer cell lines
(Elsevier, 2014-08)
It is well known the participation of oxidative stress in the induction and development of different pathologies including cancer, diabetes, neurodegeneration and respiratory disorders among others. It has been reported ...
The granulocyte colony stimulating factor (G-CSF) activates Jak/STAT and MAPK pathways in a trophoblastic cell line
(Wiley-liss, div John Wiley & Sons Inc., 2008-02)
Granulocyte colony-stimulating factor receptor (G-CSFR) has been found in placenta tissues, although its functional role has not yet been defined. In order to explore the molecular pathways induced by G-CSF in this tissue, ...
Assessing Bioenergetic Function in Response to Reactive Oxygen Species in Neural Cells
(Reactive Oxygen Species, 2020-12)
In this study, we characterized the bioenergetic response of the Lund human mesencephalic (LUHMES) cell line and a mouse astrocyte cell line to oxidative stress. Extracellular hydrogen peroxide (H2O2) levels and bioenergetic ...
Metalloproteomics analysis in human mammary cell lines treated with inorganic mercury
(Elsevier Gmbh, 2020-03)
The interest in inorganic Hg toxicity and carcinogenicity has been pointed to target organs such as kidney, brain or placenta, but only a few studies have focused on the mammary gland. In this work, analytical combination ...
Cytotoxic effects induced by combination of heliantriol B2 and dequalinium against human leukemic cell lines
(John Wiley & Sons Ltd, 2011-04)
Natural occurring compounds are considered an important source of antitumoral agents. In the present study, the cytotoxic potential of three pentacyclic triterpenes isolated from Chuquiraga erinacea (Asteraceae), against ...