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Regulation of cyclin E1 expression in human pluripotent stem cells and derived neural progeny
(Landes Bioscience, 2018-07)
Human pluripotent stem cells (hPSCs), including embryonic and induced pluripotent stem cells (hESCs and hiPSCs) show unique cell cycle characteristics, such as a short doubling time due to an abbreviated G1 phase. Whether ...
Targeting glioblastoma stem cells: The first step of photodynamic therapy
(Elsevier Science, 2021-12)
Glioblastoma is one of the most malignant types of brain cancer. Evidence suggests that within gliomas there is a small subpopulation of cells with the capacity for self-renewal, called glioma stem cells. These cells could ...
A 3D mathematical model of coupled stem cell-nutrient dynamics in myocardial regeneration therapy
(ElsevierNL, 2022)
Stem cell therapy is a promising treatment for the regeneration of myocardial tissue injured by an ischemic event. Mathematical modeling of myocardial regeneration via stem cell therapy is a challenging task, since the ...
An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells
(Wiley Blackwell Publishing, Inc, 2008-07-08)
Embryonic stem cells are a potential source for insulin‐producing cells, but existing differentiation protocols are of limited efficiency. Here, the aim has been to develop a new one, which drives development of embryonic ...
Modulation of chromatin modifying factors' gene expression in embryonic and induced pluripotent stem cells
(Academic Press Inc Elsevier Science, 2011-07)
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are a promising source of cells for regenerative medicine because of their potential of self renew and differentiation. Multiple evidences highlight ...
Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
(Cell Press, 2021-03)
Dynamic pluripotent stem cell (PSC) states are in vitro adaptations of pluripotency continuum in vivo. Previous studies have generated a number of PSCs with distinct properties. To date, however, no known PSCs have ...
Improving the Therapeutic Ability of Mesenchymal Stem/Stromal Cells for the Treatment of Conditions Influenced by Immune Cells
(Hindawi Publishing Corporation, 2021-02)
Currently, mesenchymal stem/stromal cells (MSCs) are among the most used cells in clinical trials. Whereas many characteristics of these cells have been described to date, aspects of their basic biology that may have an ...