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Dietary Salvia hispanica L. reduces cardiac oxidative stress of dyslipemic insulin-resistant rats
(National Research Council Canada-NRC Research Press, 2020-01)
Salvia hispanica L., commonly known as chia seed, has beneficial effects upon some signs of metabolic syndrome (MS), such as dyslipidemia and insulin resistance. However, its action on cardiac oxidative stress associated ...
Comment on: Kim et al. Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders. Diabetes 2011;60:3159-3168
(American Diabetes Association, 2012-07)
In the December 2011 issue of Diabetes, Kim et al. [1] reported that 4-1BB (CD137/TNFRSF9) deficiency protected against high fat diet (HFD)-induced obesity, glucose intolerance and fatty liver disease. They found that 4-1BB ...
Cacao extract enriched in polyphenols prevents endocrine-metabolic disturbances in a rat model of prediabetes triggered by a sucrose rich diet
(Elsevier, 2020-01)
Ethnopharmacological relevance: Cocoa extracts rich in polyphenols are used as potential agent for treating diabetes. Cocoa polyphenols have been proved to ameliorate important hallmarks of type-2 diabetes (T2D). They can ...
Dietary whey reduces energy intake and alters hypothalamic gene expression in obese phyto-oestrogen-deprived male rats
(Cambridge University Press, 2016-07)
Removing dietary phyto-oestrogens in adult male rats causes obesity and diabetes. As whey proteins have been reported to reduce food intakeand improve glucose homoeostasis, we investigated whether they could attenuate ...
Prenatal hyperandrogenism induces alterations that affect liver lipid metabolism
(Society for Endocrinology, 2016-07-01)
Prenatal hyperandrogenism is hypothesized as one of the main factors contributing to26 the development of polycystic ovary syndrome (PCOS). PCOS patients have high risk27 of developing fatty liver and steatosis. This study ...
Lorcaserin improves glycemic control via a melanocortin neurocircuit
(Elsevier Gmbh, 2017-10)
Objective: The increasing prevalence of type 2 diabetes (T2D) and associated morbidity and mortality emphasizes the need for a more complete understanding of the mechanisms mediating glucose homeostasis to accelerate the ...
Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons
(Elsevier Gmbh, 2016-03)
Objective: Obesity is one of the primary healthcare challenges of the 21st century. Signals relaying information regarding energy needs are integrated within the brain to influence body weight. Central among these integration ...
Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11B/CD18) in diet-induced obesity (DIO)
(Schattauer Gmbh-Verlag Medizin Naturwissenschaften, 2017-01)
Cell accumulation is a prerequisite for adipose tissue inflammation. The leukocyte integrin Mac-1 (CD11b/CD18, αMβ2) is a classic adhesion receptor critically regulating inflammatory cell recruitment. Here, we tested the ...
Metabolic syndrome and neuroprotection
(Frontiers Media S.A., 2018-04)
Introduction: Over the years the prevalence of metabolic syndrome (MetS) has drastically increased in developing countries as a major byproduct of industrialization. Many factors, such as the consumption of high-calorie ...
The neuro-endocrine-immune relationship in pulmonary and pleural tuberculosis: A better local profile in pleural fluid
(International Union Against Tuberculosis and Lung Disease, 2018-03)
BACKGROUND: Tuberculosis (TB) is a major health problem worldwide. In TB, the immune and central nervous systems modulate each other. The two main components of this network are the hypothalamic-pituitary-adrenal axis (HPA) ...