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Matrix metalloproteinases regulate extracellular levels of SDF-1/CXCL12, IL-6 and VEGF in hydrogen peroxide-stimulated human periodontal ligament fibroblasts
(Elsevier, 2015)
Periodontitis is a highly prevalent infectious disease characterized by the progressive inflammatory
destruction of tooth-supporting structures, leading to tooth loss. The underling molecular mechanisms
of the disease ...
Human periodontal ligament fibroblasts synthesize C-reactive protein and Th-related cytokines in response to interleukin (IL)-6 trans-signalling
(Blackwell, 2018)
Aim
To characterize the potential of human periodontal ligament fibroblasts (HPLF) to synthesize CRP and Th-related cytokines in response to IL-6 in periodontal health and apical inflammation.
Targeting kupffer cells with antisense oligonucleotides
(Frontiers in Bioscience, 2002)
© 2002 Frontiers in Bioscience. All rights reserved.During proinflammatory reactions such as endotoxemia, ischemia-reperfusion and immune reactions, excessive amounts of cytokines and prostanoids are released resulting in ...
Conditional TNF-alpha Overexpression in the Tooth and Alveolar Bone Results in Painful Pulpitis and Osteitis
(International & American Associations for Dental Research, 2016)
Tumor necrosis factor-alpha(TNF-alpha) is a proalgesic cytokine that is commonly expressed following tissue injury. TNF-alpha expression not only promotes inflammation but can also lead to pain hypersensitivity in nociceptors. ...
Parity history determines a systemic inflammatory response to spread of ovarian cancer in naturally aged mice
(International Society on Aging and Disease, 2017)
Aging intersects with reproductive senescence in women by promoting a systemic low-grade chronic inflammation that predisposes women to several diseases including ovarian cancer (OC). OC risk at menopause is significantly ...
Expression of proinflammatory cytokines in osteoarthritis of the temporomandibular joint
(PERGAMON-ELSEVIER SCIENCE LTD, 2008-10)
Objective: This study reports the expression of proinflammatory cytokines in temporomandibular
joint (TMJ) of patients affected with temporomandibular osteoarthritis (OA).
Design: In twelve OA of the TMJ (OA–TMJ) affected ...
MiR-155 and miR-122 expression of spermatozoa in obese subjects
(Frontiers Media S.A., 2018-05-29)
Obesity is characterized by mild chronic inflammation that is linked with impaired iron homeostasis. Studies in human and murine show that there is a transgenerational epigenetic inheritance via the gametes in obesity; ...
Protection against in vivo liver ischemia-reperfusion injury by n-3 long-chain polyunsaturated fatty acids in the rat
(2010)
N-3 polyunsaturated fatty acids (n-3 PUFA) affect inflammatory processes. This study evaluated the effects of dietary supplementation with fish oil on hepatic ischemia-reperfusion (IR) injury in the rat. Parameters of liver ...
Th1/Th17/Th22 immune response and their association with joint pain, imagenological bone loss, RANKL expression and osteoclast activity in temporomandibular joint osteoarthritis: A preliminary report
(Wiley, 2018-08)
It is well accepted that the presence of cytokines belonging to the Th1/Th17/Th22 axis of immuno-inflammatory response in the joint environment, such as IL-1, IL-17 and IL-22, respectively, are associated with pathogenesis ...