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Bioinformatic Studies for the Identification of Possible Therapeutic Targets in Amyotrophic Lateral Sclerosis (ALS) Disease: Estudios bioinformáticos para la identificación de posibles dianas terapéuticas en la enfermedad de Esclerosis Lateral Amiotrófica (ELA)
(Universidad Técnica de Ambato - FCIAL, 2023)
Drug repurposing: In-vitro anti-glycation properties of 18 common drugs
(Public Library of Science, 2018-01-04)
Drug repositioning or repurposing, i.e. identifying new indications for existing drugs, has gained increasing attention in the recent years. This approach enables the scientists to discover ?new targets? for known drugs ...
CDK5-mediated phosphorylation of p19INK4d avoids DNA damage-induced neurodegeneration in mouse hippocampus and prevents loss of cognitive functions
(Elsevier, 2014-04)
DNA damage, which perturbs genomic stability, has been linked to cognitive decline in the aging human brain, and mutations in DNA repair genes have neurological implications. Several studies have suggested that DNA damage ...
Colony-stimulating factor-1 receptor inhibition attenuates microgliosis and myelin loss but exacerbates neurodegeneration in the chronic cuprizone model
(Wiley Blackwell Publishing, Inc, 2021-12)
Multiple sclerosis (MS), especially in its progressive phase, involves early axonal and neuronal damage resulting from a combination of inflammatory mediators, demyelination, and loss of trophic support. During progressive ...
Clinical and Haematological Disorders in Cats with Natural and Progressive Infection by Feline Leukemia Virus (FeLV)
(Universidade Federal do Rio Grande do Sul, 2019)
Facial Paralysis Secondary to Hypothyroidism in a Dog
(Universidade Federal do Rio Grande do Sul, 2016)
Hepatic Encephalopathy Secondary to Chronic Liver Lesions Caused by Crotalaria incana in a Bovine
(Universidade Federal do Rio Grande do Sul, 2019)
Assessing neuraxial microstructural changes in a transgenic mouse model of early stage Amyotrophic Lateral Sclerosis by ultra‐high field MRI and diffusion tensor metrics
(Wiley, 2020-04-16)
bjective: Cell structural changes are one of the main features observed during the development of amyotrophic lateral sclerosis (ALS). In this work, we propose the useof diffusion tensor imaging (DTI) metrics to assess ...
Sera antibodies to Neospora caninum in Chilean horsesPresencia de anticuerpos sericos contra Neospora caninum en equinos en Chile
(Archivos de Medicina Veterinaria, 2004)