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Trace metals in the brain: allosteric modulators of ligand-gated receptor channels, the case of ATP-gated P2X receptors
(2008)
Zinc and copper are indispensable trace metals for life with a recognized role as catalysts in enzyme actions. We now review evidence supporting the role of trace metals as novel allosteric modulators of ionotropic receptors: ...
Mechanisms of Kappa Opioid Receptor Potentiation of Dopamine D2 Receptor Function in Quinpirole-Induced Locomotor Sensitization in Rats
(2017)
Background: Increased locomotor activity in response to the same stimulus is an index of behavioral sensitization observed in preclinical models of drug addiction and compulsive behaviors. Repeated administration of ...
The Antigen Receptor as a Driver of B-Cell Lymphoma Development and Evolution
(2017)
The expression of a functional antigen receptor is necessary for cell survival of normal B lymphocytes and most B-cell neoplasms alike. When the genetic modifications of the B-cell receptor locus fail to produce a functional ...
Propranolol restricts the mobility of single egf-receptors on the cell surface before their internalization
(PUBLIC LIBRARY SCIENCE, 2013)
The epidermal growth factor receptor is involved in morphogenesis, proliferation and cell migration. Its up-regulation during tumorigenesis makes this receptor an interesting therapeutic target. In the absence of the ligand, ...
Nerve growth factor-dependent activation of trka receptors in the human ovary results in synthesis of follicle-stimulating hormone receptors and estrogen secretion
(ISSUED FOR THE ENDOCRINE SOCIETY BY THE WILLIAMS & WILKINS CO, 2006)