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Estudos sobre liberação controlada e vetorização de drogas através de lipossomas
(2005-06-01)
The text highlights the state of research related with the application of liposomes in the control of drug delivery and drug target to infectious diseases. Liposomes have several pharmaceutical applications and this ...
Sistemas para liberação colônica: Uma alternativa para a veiculação de fármacos para efeito local ou sistêmico
(2001-12-01)
Problems related to the systemic administration of drugs, such as biodistribution, difficulty of targeting, necessity of high doses to achieve adequate levels of the drug in specific sites, toxicity, and undesirable side ...
Encapsulação da rifampicina em matrizes poliméricas flutuantes obtidas por liofilização a partir de metilcelulose e ftalato de hidroxipropilmetilcelulose. Avaliação da liberação in vitro
(2001-12-01)
Floating multiparticles for oral administration with different compositions were studied from a matricial polymeric system to obtain sustained release. The polymers used in the multiparticles constitution were methylceullose ...
Estratégias biotecnológicas para a liberação controlada de antígenos e adjuvantes em vacinas através de lipossomas
(2006-10-01)
Liposomes (LP) are colloidal systems with ability to compartmentalize therapeutic molecules in order to improve biological activity, decreases the potential toxicity, and to obtain prolonged effect. In this work it was ...
Understanding Drug Release Data through Thermodynamic Analysis
(Mdpi Ag, 2017-06-01)
Understanding the factors that can modify the drug release profile of a drug from a Drug-Delivery-System (DDS) is a mandatory step to determine the effectiveness of new therapies. The aim of this study was to assess the ...
Multiparticulate systems of pectin-chitosan: Study of swelling and drug release
(2006-10-01)
The aim of this study was to prepare multiparticulate systems of pectin:chitosan (PC:CS) and to evaluate their swelling ratio and the drug release in different environments. PC:CS particles containing triamcinolone were ...
Preparation and characterization of poly(ε-caprolactone) nanospheres containing the local anesthetic lidocaine
(2013-01-01)
The objective of this work was to develop a modified release system for the local anesthetic lidocaine (LDC), using poly(ε-caprolactone) (PCL) nanospheres (NSs), to improve the pharmacological properties of the drug when ...
Preparation and characterization of poly(e-caprolactone) nanospheres containing the local anesthetic lidocaine
(Wiley-blackwellHobokenEUA, 2013)
LC Evaluation of In Vitro Release of AZT from Microemulsions
(Vieweg, 2009-06-01)
A reversed phase LC method was developed and validated to analyze the in vitro release of AZT from microemulsions. A mobile phase of acetonitrile:water (15:85) was used. The method validation showed good selectivity and ...
Preparation and physicochemical characterization of drug loaded in castor oil-based polyurethane
(Springer, 2020-02-01)
Castor oil is an environmentally friendly alternative to hydrocarbon-based feedstocks for the synthesis of polyurethanes due to its major constituent, ricinoleic acid. This work aimed to obtain and characterize castor ...