Buscar
Mostrando ítems 1-10 de 10
Sclerostin And Insulin Resistance In Prediabetes: Evidence Of A Cross Talk Between Bone And Glucose Metabolism
(AMER DIABETES ASSOCALEXANDRIA, 2015)
Low sclerostin levels: a predictive marker of persistent inflammation in ankylosing spondylitis during anti-tumor necrosis factor therapy?
(2012)
Abstract
Introduction
Sclerostin levels have been reported to be low in ankylosing spondylitis (AS), but there is no data ...
Serum sclerostin is an independent predictor of mortality in hemodialysis patients
(BMC, 2014-12-02)
Background
Sclerostin (Scl) has recently emerged as a novel marker of bone remodeling and vascular calcification. However, whether high circulating Scl is also a risk factor for death is not well established. ...
Serum sclerostin is an independent predictor of mortality in hemodialysis patients
(2014-12-02)
Abstract
Background
Sclerostin (Scl) has recently emerged as a novel marker of bone remodeling and vascular calcification. However, whether high circulating Scl is also a risk ...
Peritoneal dialysis per se is a risk factor for sclerostin-associated adynamic bone disease
(Nature Publishing Group, 2015-05-01)
Chronic kidney disease-mineral bone disorder (CKD-MBD) is a complex syndrome influenced by various factors, such as age, CKD etiology, uremic toxins, and dialysis modality. Although extensively studied in hemodialysis (HD) ...
Bariatric Roux-En-Y Gastric Bypass Surgery: Adipocyte Proteins Involved in Increased Bone Remodeling in Humans
(2017-07-01)
Purpose: Bariatric surgery has been associated with bone remodeling changes. The action of adipokines on the expression of receptor activator of nuclear factor kappa β ligand (RANKL) and osteoprotegerin (OPG) and on an ...
Renal osteodystrophy in the obesity era: Is metabolic syndrome relevant?
(2017-07-01)
Background Observational studies have shown a beneficial effect of obesity on bone health; however, most of those studies were not based on bone biopsies. Metabolic syndrome (MetS) could have an effect on bone remodeling. ...
Fibroblast-secreted trophic factors contribute with ECM remodeling stimulus and upmodulate osteocyte gene markers in osteoblasts
(2020-01-01)
As osteogenesis is a multifactorial mechanism, we wonder whether osteoblast-induced extracellular matrix (ECM) remodeling might be modulated by trophic factors released by fibroblasts in a paracrine signaling manner. To ...
Greater Gains in Spine and Hip Strength for Romosozumab Compared With Teriparatide in Postmenopausal Women With Low Bone Mass
(American Society for Bone and Mineral Research, 2017-09)
Romosozumab is a monoclonal antibody that inhibits sclerostin and has been shown to reduce the risk of fractures within 12 months. In a phase II, randomized, placebo-controlled clinical trial of treatment-naïve postmenopausal ...