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Solid dispersions with hydrogenated castor oil increase solubility, dissolution rate and intestinal absorption of praziquantel
(2010-01-01)
The solubility behavior of drugs remains one of the most challenging aspects in formulation development. Solid Dispersion (SD) has tremendous potential for improving drug solubility. Although praziquantel (PZQ) is the first ...
Solid dispersions with hydrogenated castor oil increase solubility, dissolution rate and intestinal absorption of praziquantel
(Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, 2010)
The solubility behavior of drugs remains one of the most challenging aspects in formulation development. Solid Dispersion (SD) has tremendous potential for improving drug solubility. Although praziquantel (PZQ) is the first ...
Solid dispersions with hydrogenated castor oil increase solubility, dissolution rate and intestinal absorption of praziquantel
(Universidade de São Paulo (USP), Conjunto Quimicas, 2010-07-01)
The solubility behavior of drugs remains one of the most challenging aspects in formulation development. Solid Dispersion (SD) has tremendous potential for improving drug solubility. Although praziquantel (PZQ) is the first ...
Preparation and characterisation of Dextran-70 hydrogel for controlled release of praziquantel
(Universidade de São Paulo (USP), Faculdade de Ciências Farmacêuticas, 2013-03-01)
Um hidrogel foi desenvolvido a partir de dextrano 70 kDa (DEX-70) e praziquantel incorporado (PZQ) como fármaco modelo. Propriedades biofarmacêuticas, como solubilidade e velocidade de dissolução, foram analisadas no ...
Development and physicochemical characterization of solid dispersions containing praziquantel for the treatment of schistosomiasis
(2017-02-01)
Praziquantel (PZQ) is an anthelminthic agent active against parasitic flatworms of the Schistosoma type and the most important drug for the treatment and morbidity control of schistosomiasis. In this study, a high-performance ...
Development and Evaluation of Praziquantel Solid Dispersions in Sodium Starch Glycolate
(Pharmacotherapy GroupBenin CityNigéria, 2013)
Preparation and Characterization of Amylose Inclusion Complexes for Drug Delivery Applications
(Wiley-Blackwell, 2016-01-01)
Amylose complexes with nimesulide (NMS) and praziquantel (PZQ) were prepared by a simple and low cost method, so that high yield (>57%) and drug content (up to 68.16%) were achieved. The influence of drug: polymer ratio, ...
Development and evaluation of praziquantel solid dispersions in sodium starch glycolate
(2013-04-01)
Purpose: To develop and characterize solid dispersions of praziquantel (PZQ) with sodium starch glycolate (SSG) for enhanced drug solubility. Methods: PZQ solid dispersion (SD) was prepared using co-precipitation method ...