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NEUREGULINS 1-ALPHA AND 1-BETA ON THE REGENERATION THE PERIPHERAL NERVES
(ATHA COMUNICACAO & EDITORA, 2010)
Objective: To evaluate the effect of the neuregulins 1-alpha and 1-beta on the regeneration the sciatic nerves of male adult C57BL/6J mice, using the tubulization technique. Methods: Eighteen animals were used, divided ...
Neuregulin-1/erbB activities with focus on the susceptibility of the heart to anthracyclines
(Baishideng Publishing Group, 2014-07)
Neuregulin-1 (NRG1) signaling through the tyrosine kinase receptors erbB2 and erbB4 is required for cardiac morphogenesis, and it plays an essential role in maintaining the myocardial architecture during adulthood. The ...
Interleukin-6 and neuregulin-1 as regulators of utrophin expression via the activation of NRG-1/ErbB signaling pathway in mdx cells
(Elsevier B.V., 2017)
© 2016 Elsevier B.V. Duchenne muscular dystrophy (DMD) is a neuromuscular disease originated by mutations in the dystrophin gene. A promising therapeutic approach deals with functional substitution of dystrophin by utrophin, ...
Neuregulinas 1-alfa e 1-beta na regeneração de nervos periféricos
(Atha Comunicação & Editora, 2010)
OBJETIVO: Avaliar o efeito das neuregulinas 1-alfa e 1-beta na regeneração de nervos ciáticos de camundongos C57BL/6J, adultos, machos, através da técnica de tubulização. MÉTODOS: Utilizaram-se 18 animais, divididos em 3 ...
Novel therapies targeting cardioprotection and regeneration
(Bentham Science Publishers, 2017)
Cardiovascular disease is the leading cause of death worldwide. The heart is susceptible to pathologies that impact the myocardium directly, such as myocardial infarction and consequent heart failure, as well as conditions ...
In vivo and in vitro genetic evidence of involvement of neuregulin 1 in immune system dysregulation
(J Mol Med (Berl). 2010 November ; 88(11): 1133–1141, 2010-11)
Neuregulin 1 (NRG1) has been implicated in several disorders including breast cancer, multiple sclerosis, and schizophrenia. Also, recent evidence suggests that NRG1 may play a role in regulation of inflammation and immune ...
Cooverexpression Of Erbb1 And Erbb4 Receptors Predicts Poor Clinical Outcome In Pn+ Oral Squamous Cell Carcinoma With Extranodal Spread
(Springer Science and Business Media Netherlands, 2014)