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Melatonin-Loaded Nanocarriers: New Horizons for Therapeutic Applications
(Multidisciplinary Digital Publishing Institute, 2021-06)
The use of nanosized particles has emerged to facilitate selective applications in medicine. Drug-delivery systems represent novel opportunities to provide stricter, focused, and fine-tuned therapy, enhancing the therapeutic ...
Pulmonary drug delivery: A review on nanocarriers for antibacterial chemotherapy
(Oxford University Press, 2015-07)
As the WHO stated, lower respiratory infections are the third leading cause of death. In addition, it is remarkable that antimicrobial resistance represents a huge threat. Thus, new therapeutic weapons are required. Among ...
Nanocarriers for effective delivery of benznidazole and nifurtimox in the treatment of chagas disease: A review
(Elsevier Science, 2019-10)
Neglected tropical diseases (NTDs) constitute a group of infectious diseases prevalent in countries with tropical and subtropical climate that affect the poorest individuals and produce high chronic disability associated ...
Bioaccessibility of folic acid in egg white nanocarriers and protein digestion profile in solution and in emulsion
(Elsevier Science, 2019-08)
The objective of this work is to assess bioaccessibility of folic acid in egg white (EW) nanocarriers after digestion of solutions and emulsions containing the vitamin-protein complexes. Furthermore, the influence of folic ...
More than just size: Challenges and opportunities of hybrid dendritic nanocarriers
(Bentham Science Publishers, 2017-04)
Background: Dendrimers and hyperbranched polymers are emerging polymer architectures that attract increasing attention due to their unique topological structure and interesting physicochemical properties. Their enormous ...
Overcoming biological barriers with block copolymers-based self-assembled nanocarriers. Recent advances in delivery of anticancer therapeutics
(Frontiers Media S.A., 2020-11)
Cancer is one of the most common life-threatening illness and it is the world’s second largest cause of death. Chemotherapeutic anticancer drugs have many disadvantages, which led to the need to develop novel strategies ...
Synthetic and biological identities of layered double hydroxides nanocarriers functionalized with risedronate
(Elsevier Science, 2020-12-01)
Layered double hydroxide nanoparticles (LDH-NP) provide new therapeutic opportunities to improve drug distribution, stability, and effectivity. Nevertheless, these LDH-NP present a different behavior in biological medium ...
Evaluation of ovalbumin nanocarriers to promote the vehiculization and antifungal properties of cinnamaldehyde in aqueous media
(Elsevier Science, 2021-11)
This paper is aimed to evaluate the vehiculization of trans-cinnamaldehyde (CIN) through the formation of complexes with ovalbumin (OVA) and heat-induced OVA nanoparticles (OVAn) to promote its application in aqueous media. ...
Self-assembled micelles of the (lipo) glycopeptides, teicoplanin, as taxane nanocarriers
(IOP Publishing, 2021-11)
The use of nanoparticles is one of the strategies currently studied to minimize the toxicity and lack of tissue specificity of many cancer drugs used in chemotherapy. In this research the physicochemical and biological ...
Effect of the protein corona on the colloidal stability and reactivity of LDH-based nanocarriers
(Royal Society of Chemistry, 2016-03-15)
The physicochemical properties of drug nanocarriers such as layered double hydroxide nanoparticles (LDH-NPs) determine their circulation times in biological media and their interaction with the targeted cells. Nevertheless, ...