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Reduced cancer mortality at high altitude: The role of glucose, lipids, iron and physical activity
(Elsevier, 2017)
Residency at high altitude (HA) demands adaptation to challenging environmental conditions with hypobaric hypoxia being the most important one. Epidemiological and experimental data suggest that chronic exposure to HA ...
Prenatal hyperandrogenism induces alterations that affect liver lipid metabolism
(Society for Endocrinology, 2016-07-01)
Prenatal hyperandrogenism is hypothesized as one of the main factors contributing to26 the development of polycystic ovary syndrome (PCOS). PCOS patients have high risk27 of developing fatty liver and steatosis. This study ...
Activation of peroxisome proliferator nuclear receptors regulates lipid metabolism in the placenta
(Galenos Yayincilik, 2007-09)
OBJECTIVE: Peroxisome proliferator activated receptors (PPARs), known regulators of lipid homeostasis in different tissues, are crucial during placental development. In this work we aim to determine whether PPARs activation ...
Lipids at the crossroad of α-synuclein function and dysfunction: Biological and pathological implications
(Frontiers Media S.A., 2019-05-01)
Since its discovery, the study of the biological role ofα-synuclein and its pathologicalimplications has been the subject of increasing interest. The propensity to adoptdifferent conformational states governing its aggregation ...
A descriptive study of the occurrence and significance of lipids in Taenia hydatigena eggs
(Elsevier Science, 2010-04)
The aim of this work was to investigate the lipid content of Taenia hydatigena eggs and to evaluate the role of lipids in the maintenance of embryo viability. The total lipid content of the egg was 4.5% (w/w). Five classes ...
PPARalpha agonists regulate lipid metabolism and nitric oxide production and prevents placental overgrowth in tern in placentas from diabetic rats
(BioScientifica, 2011-06)
Maternal diabetes impairs fetoplacental metabolism and growth. Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor capable of regulating lipid metabolism and inflammatory pathways. In this study, we ...
Comprehensive analysis of a metabolic model for lipid production in Rhodosporidium toruloides
(Elsevier Science, 2018-08)
The yeast Rhodosporidium toruloides has been extensively studied for its application in biolipid production. The knowledge of its metabolism capabilities and the application of constraint-based flux analysis methodology ...
Nuclear-lipid-droplet proteome: carboxylesterase as a nuclear lipase involved in lipid-droplet homeostasis
(Elsevier, 2021-03)
Nuclear-lipid droplets (nLD)—a dynamic cellular organelle that stores neutral lipids, within the nucleus of eukaryotic cells—consists of a hydrophobic triacylglycerol –cholesterol-ester core enriched in oleic acid (OA) ...
Effect of Conjugated Linoleic Acids on Nutritional Status and Lipid Metabolism in Rats Fed Linoleic-Acid-Deprived Diets
(Wiley VCH Verlag, 2019-03)
This study aims to investigate the effect of conjugated linoleic acid (CLA) on nutritional parameters and triacylglycerol (TAG) regulation in male Wistar rats fed linoleic acid (LA)-deprived (−LA) diets compared to LA-enriched ...
In silico optimization of lipid production in Rhodosporidium toruloides by gene knockout strategies
(Elsevier Science, 2019-04)
Microbial lipids are being extensively studied as an alternative to vegetable oils in biodiesel production. For the biotechnological production of biolipids, efficient processes capable of obtaining significant biomass ...