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Frequency of human platelet antigens in oncohematological patients with thrombocytopenia and the probability of incompatibility to platelet transfusionsFrequência dos antígenos plaquetários humanos (HPA) em pacientes trombocitopênicos e predisposição à incompatibilidade transfusional
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea, 2012)
OBJECTIVE: The objective of this study was to evaluate the frequencies of human platelet antigens in oncohematological patients with thrombocytopenia and to analyze the probability of their incompatibility with platelet ...
Human platelets antigens influence the viral load of platelets after the interaction of the platelets with HCV and HIV in vitro
(Soc Brasileira Medicina Tropical, 2016-07-01)
Introduction: In this study, we evaluated hepatitis C virus (HCV) and human immunodeficiency virus (HIV) - platelet interactions in vitro as well as human platelets antigen (HPA) polymorphisms. Methods: Platelets were ...
Allelic Frequencies of HPA-1 to 5 Human Platelet Antigens in Patients Infected With Hepatitis C Virus
(Wiley-liss, 2009-04-01)
Studies have suggested that hepatitis C virus (HCV) may infect not only hepatocytes but may also be carried by platelets. Platelets express more than 20 polymorphic antigenic determinants on their surface, which are called ...
Allelic Frequencies of HPA-1 to 5 Human Platelet Antigens in Patients Infected With Hepatitis C Virus
(Wiley-liss, 2009-04-01)
Studies have suggested that hepatitis C virus (HCV) may infect not only hepatocytes but may also be carried by platelets. Platelets express more than 20 polymorphic antigenic determinants on their surface, which are called ...
Avaliação dos polimorfismos HPA em plaquetas expostas in vitro ao ZIKV
(Universidade Estadual Paulista (Unesp), 2021-05-27)
O ZIKA vírus é um arbovírus da família Flaviviridae e gênero flavivirus, possuindo grandes semelhanças genéticas e estruturais a outros arbovírus relevantes na área da saúde. A infecção por este patógeno está associada a ...
Human Platelet Antigen Genotype Is Associated With Progression of Fibrosis in Chronic Hepatitis C
(Wiley-Blackwell, 2012-01-01)
Although progression of fibrosis in the chronic hepatitis C depends on environmental, viral, and host factors, genetic polymorphisms have been associated recently with this progression, including the expression of integrins, ...
Human Platelet Antigen Genotype Is Associated With Progression of Fibrosis in Chronic Hepatitis C
(Wiley-Blackwell, 2012-01-01)
Although progression of fibrosis in the chronic hepatitis C depends on environmental, viral, and host factors, genetic polymorphisms have been associated recently with this progression, including the expression of integrins, ...
Human platelet antigen-3 polymorphism as a risk factor for rheumatological manifestations in hepatitis C
(Soc Brasileira Medicina Tropical, 2020-01-01)
Introduction: Hepatitis C virus (HCV) infection is involved in the pathogenesis of autoimmune and rheumatic disorders. Although the human platelet antigens (HPA) polymorphism are associated with HCV persistence, they have ...
Establishment of the first platelet-donor registry in Argentina
(Società Italiana di Medicina Trasfusionale e Immunoematologia, 2020-07)
Background: Platelet transfusions are necessary to prevent and treat haemorrhages in thrombocytopenic patients or those with severe platelet dysfunction. In Latin American countries, including Argentina, blood supplies ...
HPA-1a/1b could be considered a molecular predictor of poor prognosis in chronic hepatitis C
(2019-01-01)
Introduction: HPA polymorphism has been associated with HCV presence and fibrosis progression in chronic hepatitis C. However, it is unknown if there is an association between HPA-1 polymorphism and hepatocellular carcinoma ...