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Resistencia y sensibilidad a Warfarina
(Pereira: AREANDINA. Fundación Universitaria del Área Andina, 2010-04)
La warfarina, el anticoagulante oral de mayor prescripción en el mundo, es un fármaco difícil de manejar por su estrecho margen terapéutico, amplia gama de interacciones y gran variabilidad inter-individual en la respuesta. ...
Caracterización del gen de la dopamina B-hidroxilasa en población mestiza colombiana
(Pereira: AREANDINA. Fundación Universitaria del Área Andina, 2013-09)
La dopamina B-hidroxilasa cataliza la conversión de dopamina en norepinefrina y es blanco promisorio de intervenciones farmacológicas. Polimorfismos del gen DBH son responsables de las diferencias individuales en el tono ...
Superoxide dismutase, catalase, glutathione peroxidase and gluthatione S-transferases M1 and T1 gene polymorphisms in three Brazilian population groups
(Sociedade Brasileira de Genética, 2017)
CYP2D6 Allele Frequency in Five Malaria Vivax Endemic Areas From Brazilian Amazon Region
(Frontiers Media, 2022)
Pharmacogenetics and antiepileptic drug metabolism: Implication of genetic variants in cytochromes P450 [Farmacogenética y metabolismo de fármacos antiepilépticos: Implicación de variantes genéticas en citocromos P1450]
(2013)
Introduction. Antiepileptic drugs (AEDs) are used for the seizures control in patients with epilepsy, however 20-30% of epileptic patients are drug resistant. Several factors contributing to the variability of the AEDs ...
DNA and Oxidative Damages Decrease After Ingestion of Folic Acid in Patients with Type 2 Diabetes
(2012)
Background and Aims: Type 2 diabetes mellitus (T2DM) is a chronic degenerative disease that promotes autoxidation of sugars, leading to the production of reactive oxygen species. This damage occurs especially at the level ...
Methylphenidate lacks genotoxic effects in mouse peripheral blood erythrocytes
(2011)
Methylphenidate (MPH; Ritalin®; Novartis Pharmaceuticals, Inc., Basel, Switzerland) has been prescribed to treat attention deficit/hyperactivity disorder (ADHD) since its approval by the U.S. Food and Drug Administration ...
Pharmacogenetics and antiepileptic drug metabolism: Implication of genetic variants in cytochromes P450 [Farmacogenética y metabolismo de formacos antiepilépticos: Implicación de variantes genéticas en citocromos P1450]
(2005)
In this study, we evaluated the effect of prostaglandin E2 (PGE2) on renal and hepatic function using an experimental cirrhosis model plus acute liver damage (ALD). Male Wistar rats treated with carbon tetrachloride (CCl4) ...
DNA and Oxidative Damages Decrease After Ingestion of Folic Acid in Patients with Type 2 Diabetes
(2003)
The seasonal variation in the diversity of ichthyoplankton was analyzed from samples collected monthly during a year cycle off the central Pacific coast of Mexico. Samples were collected using a Bongo net at 12 stations ...