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Glyphosate induces epithelial mesenchymal transition-related changes in human endometrial Ishikawa cells via estrogen receptor pathway
(Elsevier Ireland, 2020-04)
Glyphosate based herbicides are the most commonly used herbicide in the world. We aimed to determine whether glyphosate (Gly) induces epithelial mesenchymal transition (EMT) - related changes in a human endometrial carcinoma ...
Estrogen and Progesterone Receptors and COX-2 Expression in Endometrial Biopsy Samples During Maternal Recognition of Pregnancy in Llamas (Lama glama)
(Wiley Blackwell Publishing, Inc, 2015-12)
Endometrial expression of oestrogen receptor-a (ERa),progesterone receptor (PR) and cyclooxigenase-2 (COX-2)was evaluated in non-pregnant and pregnant llamas during theperiod when luteolysis/maternal recognition of pregnancy ...
Estrogen regulates endometrial cell cytoskeletal remodeling and motility via focal adhesion kinase
(Elsevier Science Inc, 2011-02)
Objective: To explore the effects of 17β-estradiol (E2) on cytoskeletal remodeling and motility of endometrial stromal cells (ESC) and Ishikawa cells and to characterize the role of focal adhesion kinase (FAK) in these ...
Induction of uterine hyperplasia after cafeteria diet exposure
(Elsevier Ireland, 2018-12)
Our aim was to evaluate whether chronic administration of CAF affects the uterus and induces the morphological and molecular changes associated with endometrial hyperplasia. Female Wistar rats exposed to CAF from weaning ...
Progestin activation of nongenomic pathways via cross talk of progesterone receptor with estrogen receptor beta induces proliferation of endometrial stromal cells
(Endocrine Society, 2005-12)
Uterine decidualization is characterized by stromal cell proliferation and differentiation, which are controlled by ovarian hormones estradiol and progesterone. Here we report that the proliferative response of UIII rat ...
Ulipristal acetate interferes with actin remodeling induced by 17β-estradiol and progesterone in human endometrial stromal cells
(Frontiers Research Foundation, 2018-06)
Ulipristal acetate (UPA) is a selective progesterone receptor modulator (SPRM) used for emergency contraception and for the medical management of symptomatic uterine fibroids (UF). Treatment with UPA turns in amenorrhea ...
Evidence for shared molecular pathways of dysregulated decidualization in preeclampsia and endometrial disorders revealed by microarray data integration
(Federation of American Societies for Experimental Biology, 2019-11)
Microarray data of chorionic villous samples (CVSs) obtained from women of ~11.5 gestational weeks who developed preeclampsia with severe features (sPE; PE-CVS) revealed a molecular signature of impaired endometrial ...
Endometrial expression of key genes related to fertility in repeat breeder and non-repeat breeder cows
(Wiley Blackwell Publishing, Inc, 2020-11)
The aim of the present study was to compare the endometrial gene expression of epidermal growth factor receptor (EGFR), nodal growth differentiation factor (NODAL), prostaglandin-endoperoxide synthase 2 (PTGS2), oestrogen ...
Neonatal exposure to low doses of endosulfan induces implantation failure and disrupts uterine functional differentiation at the pre-implantation period in rats
(Elsevier Ireland, 2015-02)
We investigated whether neonatal exposure to low doses of endosulfan affects fertility and uterine functional differentiation at pre-implantation in rats. Newborn female rats received the vehicle, 0.2 μg/kg/d of ...
Enhanced cyclooxygenase-2 expression levels and metalloproteinase 2 and 9 activation by Hexachlorobenzene in human endometrial stromal cells
(Pergamon-Elsevier Science Ltd, 2016-06)
Hexachlorobenzene (HCB) is an organochlorine pesticide that induces toxic reproductive effects in laboratory animals. It is a dioxin-like compound and a weak ligand of the aryl hydrocarbon receptor (AhR). Endometriosis is ...