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Enantioselective biotransformation of propranolol to the active metabolite 4-hydroxypropranolol by endophytic fungi
(Sociedade Brasileira de Química, 2011)
The enantioselective biotransformation of propranolol (Prop) by the endophytic fungi Phomopsis sp., Glomerella cingulata, Penicillium crustosum, Chaetomium globosum and Aspergillus fumigatus was investigated by studying ...
Protection studies of Saccharomyces cerevisiae cells for the use in reduction reactions in organic media.
(Soc Brasileira QuimicaSao PauloBrasil, 2002)
Highly enantioselective reduction of the C-C double bond of N-phenyl-2-methyl- and N-phenyl-2,3-dimethyl-maleimides by fungal strains
(Pergamon-Elsevier Science Ltd, 2009-05)
The CAC double bond of non-substituted and substituted maleimides were hydrogenated to the corresponding succinimides by fungal strains. 2- and 2,3-methylated-phenyl-maleimides were enantioselectively reduced to ...
Enantioselective analysis of oxybutynin and N-desethyloxybutynin with application to an in vitro biotransformation study
(ELSEVIER SCIENCE BV, 2008)
An enantioselective method using liquid-phase microextraction (LPME) followed by HPLC analysis was developed for the determination of oxybutynin (OXY) and its major metabolite N-desethyloxybutynin (DEO) in rat liver ...
Enantioselective Analysis of Fluoxetine and Norfluoxetine by LC in Culture Medium for Application in Biotransformation Studies Employing Fungi
(VIEWEG, 2009)
A liquid chromatography method is described for the analysis of fluoxetine and norfluoxetine enantiomers in fungi cultures. The analytes were separated simultaneously by LC employing a serial system. The resolution was ...
Enantiomeric behaviour of albendazole and fenbendazole sulfoxides in domestic animals: Pharmacological implications
(Elsevier, 2009-09)
Albendazole and fenbendazole are methylcarbamate benzimidazole anthelmintics extensively used to control gastrointestinal parasites in domestic animals. These parent compounds are metabolised to albendazole sulfoxide and ...
Microbial Diversification Of Diels–alder Cycloadducts By Whole Cells Of Penicillium Brasilianum
(Springer International Publishing, 2016)
Effects of Chirality on the Antifungal Potency of Methylated Succinimides Obtained by Aspergillus fumigatus Biotransformations. Comparison with Racemic Ones
(Molecular Diversity Preservation International, 2013-05)
Eighteen (3R) and (3R,4R)-N-phenyl-, N-phenylalkyl and N-arylsuccinimides were prepared with high enantioselectivity by biotransformation of maleimides with A. fumigatus. This environmentally friendly, clean and economical ...