Now showing items 1-10 of 1068
(Springer Nature Switzerland AG, 2018)
Membrane transporters perform a central function in many essential body functions, including traffic and compartmentalization of physiologic compounds, absorption of physiologic compounds (and, occasionally, structurally ...
An Epidemiological Study of Drug Resistance and Resistance Genes in Bovine Escherichia coli Isolates in Heilongjiang Province of China
(Universidade Federal do Rio Grande do Sul, 2018)
Genotypes of Mycobacterium tuberculosis in patients at risk of drug resistance in Bolivia
(Elsevier Science, 2013-04)
Bolivia ranks among the 10 Latin American countries with the highest rates of tuberculosis (TB) and multidrug resistant (MDR) TB. In view of this, and of the lacking information on the population structure of Mycobacterium ...
Development and Validation of a Computational Model Ensemble for the Early Detection of BCRP/ABCG2 Substrates during the Drug Design Stage
(American Chemical Society, 2017-08)
Breast Cancer Resistance Protein (BCRP) is an ATP-dependent efflux transporter linked to the multidrug resistance phenomenon in many diseases such as epilepsy and cancer and a potential source of drug interactions. For ...
Performance of four transport and storage systems for molecular detection of multidrug-resistant tuberculosis
(Public Library of Science, 2015-10)
Background Detection of drug-resistant tuberculosis is essential for the control of the disease but it is often hampered by the limitation of transport and storage of samples from remote locations to the reference laboratory. ...
Molecular and phenotypic characterisation of Mycobacterium tuberculosis resistant to anti-tuberculosis drugs
(International Union Against Tuberculosis and Lung Disease, 2013-08)
SETTING: Dr Cetrángolo Hospital, Buenos Aires, Argentina. OBJECTIVES: To characterise drug-resistant (DR), multidrug-resistant (MDR-) and extensively drug-resistant (XDR-) Mycobacterium tuberculosis isolates, and identify ...
Drug transfer into target helminth parasites
The pharmacokinetics of an anthelmintic drug includes the time course of drug absorption, distribution, metabolism and elimination from the host and determines the concentration of the active drug that reaches the location ...
Overcoming drug resistance with on-demand charged thermoresponsive dendritic nanogels
(Future Medicine, 2016-11-23)
To develop nanogels (NG) able to modulate the encapsulation and release of drugs, in order to circumvent drug resistance mechanisms in cancer cells. Materials & methods: Poly-N-isopropylacrylamide-dendritic polyglycerol ...
Prevalence of Antimicrobial Resistance in Bacterial Isolates from Dogs and Cats in a Veterinary Diagnostic Laboratory in Colombia from 2016–2019
(MDPICentro de Investigaciones Básicas y Aplicadas en Veterinaria (CIBAV)Basilea, Suiza, 2022)