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Interaction of cyclic and linear labaditin peptides with anionic and zwitterionic micelles
(2014)
Conformational changes of the cyclic (Lo) peptide Labaditin (VWTVWGTIAG) and its linear analogue (L1) promoted by presence of anionic sodium dodecyl sulfate (SDS) and zwitterionic L-α-Lysophosphatidylcholine (LPC) micelles ...
Jatrophidin I, a cyclic peptide from Brazilian Jatropha curcas L.: Isolation, characterization, conformational studies and biological activity
(Elsevier B.V., 2014-11-01)
A cyclic peptide, jatrophidin I, was isolated from the latex of Jatropha curcas L. Its structure was elucidated by extensive 2D NMR spectroscopic analysis, with additional conformational studies performed using Molecular ...
STAT1, STAT3 and p38MAPK are involved in the apoptotic effect induced by a chimeric cyclic interferon-α2b peptide
(Elsevier Inc, 2010-02)
In the search of mimetic peptides of the interferon-α2b molecule (IFN-α2b), we have previously designed and synthesized a chimeric cyclic peptide of the IFN-α2b that inhibits WISH cell proliferation by inducing an apoptotic ...
Combinatorial Library Screening Coupled to Mass Spectrometry toIdentify Valuable Cyclic Peptides
(Wiley, 2016-01)
Combinatorial library screening coupled to mass spectrometry (MS) analysis isa practical approach to identify useful peptides. Cyclic peptides can have highbiological activity, selectivity, and affinity for target proteins, ...
Peptídeos cíclicos de biomassa vegetal: características, diversidade, biossíntese e atividades biológicas
(Sociedade Brasileira de Química, 2009-01-01)
Natural peptides are outstanding as the most promising macromolecules in the search for new drugs, especially those of cyclic nature. The higher plants revealed a very peculiar composition of their cyclic peptides, which ...
The importance of cyclic structure for Labaditin on its antimicrobial activity against Staphylococcus aureus
(Elsevier B.V., 2016-12-01)
Antimicrobial resistance has reached alarming levels in many countries, thus leading to a search for new classes of antibiotics, such as antimicrobial peptides whose activity is exerted by interacting specifically with the ...
Interaction of cyclic and linear Labaditin peptides with anionic and zwitterionic micelles
(Elsevier B.V., 2015-01-15)
Conformational changes of the cyclic (Lo) peptide Labaditin (VWTVWGTIAG) and its linear analogue (L-1) promoted by presence of anionic sodium dodecyl sulfate (SDS) and zwitterionic L-alpha-Lysophosphatidylcholine (LPC) ...
Labaditin, a cyclic peptide with rich biotechnological potential: preliminary toxicological studies and structural changes in water and lipid membrane environment
(Springer, 2011-01-01)
Cyclic peptides isolated from the plants of the Euphorbiaceae family have been largely studied due to their rigid conformation, which is considered significant for biologic activity. The peptide Labaditin (L(0)) and its ...
Alterations in cyclic GMP levels in preeclampsia may reflect increased B-type natriuretic peptide levels and not impaired nitric oxide activity
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
Objectives: We compared nitrite, B-type natriuretic peptide (BNP), and cGMP levels in preeclamptic with those found in healthy pregnant. Methods: We studied 21 healthy pregnant and 27 preeclamptic. Plasma cGMP and BNP ...
The self-assembly of redox active peptides: Synthesis and electrochemical capacitive behavior
(2016-05-01)
The present work reports on the synthesis of a redox-tagged peptide with self-assembling capability aiming applications in electrochemically active capacitive surfaces (associated with the presence of the redox centers) ...