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Different responses to doxorubicin-induced chromosome aberrations in Brazilian deer species
(Funpec-editora, 2010-01-01)
The tendency toward chromosome fragility is one of the theories that may explain chromosome variation in brocket deer species (genus Mazama). We tested doxorubicin as an inducer of chromosome aberrations in lymphocytes of ...
Cytogenetics of three breeds of river buffalo (Bubalus bubalis L.), with evidence of a fragile site on the X chromosome
(Elsevier B.V., 1998-02-01)
The cytogenetic study of 182 river buffalo (Bubalus bubalis L., 2n=50) of Murrah, Mediterranean and Jaffarabadi breeds, from the State of São Paulo, was carried out to characterize their chromosomes and to detect possible ...
IDENTIFICATION OF COMMON FRAGILE SITES IN CHROMOSOMES OF 2 SPECIES OF BAT (CHIROPTERA, MAMMALIA)
(Elsevier B.V., 1994-01-01)
In the karyotypes of the bat species Molossus ater and M molossus, spontaneous and bromodeoxyuridine (BrdU)- or aphidicolin (APC)-sensitive fragile sites were located. Four chromosome regions harbored APC-sensitive fragile ...
Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites
(Ferrata Storti Foundation, 2000-10)
Increased frequencies of spontaneous and bromodeoxyuridine induced breakages with a non-random distribution of breakpoints were found in patients with chronic myeloid scientific correspondence 1105 Haematologica vol. ...
Identifying Mazama gouazoubira (Artiodactyla; Cervidae) chromosomes involved in rearrangements induced by doxorubicin
(2017-01-01)
The process of karyotype evolution in Cervidae from a common ancestor (2n = 70, FN = 70) has been marked by complex chromosomal rearrangements. This ancestral karyotype has been retained by the current species Mazama ...
Velocardiofacial syndrome with a rare t(2;22)
(2007-07-01)
Rearrangements involving chromosomes 2 and 22 were described not only as acquired abnormalities in a variety of human neoplasias but also in the constitutional karyotype suggesting the existence of a greater fragility in ...
Fragile X syndrome. Clinical analysis of 300 Chilean patients with unspecific mental retardation Síndrome de X frágil. Análisis clínico en 300 pacientes con retardo mental inespecífico en la población chilena
(1998)
Background: Fragile X syndrome is the most important cause of sex linked mental retardation and the second of chromosomal origin, after Down syndrome. Aim: To apply the modified Hagerman score to patients with mental ...
Expression of common fragile sites in two Ceboidea species: Saimiri boliviensis and Alouatta caraya (Primates: Platyrrhini)
(BioMed Central, 2000-02)
Fragile sites are points of preferential breakage that may be involved in chromosome rearrangements. Induction of common fragile sites (c-fra) and spontaneous breakage were analyzed in two New World Monkeys species: Saimiri ...