Buscar
Mostrando ítems 1-10 de 26
Organogenesis from leaf and internode explants of Ophiorrhiza prostrata, an anticancer drug (camptothecin) producing plant
(Pontificia Universidad Católica de Valparaíso, 2007)
The effect of siRNA-Egr-1 and camptothecin on growth and chemosensitivity of breast cancer cell lines
(2010)
We have examined the effects of a siRNA targeting the Egr-1, alone or in combination with the breast cancer therapeutic camptothecin (Cpt), in suppressing breast cancer cell survival and anchorage-independent growth in the ...
Self-aggregates of 3,6-O,O’-dimyristoylchitosan derivative are effective in enhancing the solubility and intestinal permeability of camptothecin
(2017-12-01)
The aim of this work was to investigate the potential of a new 3,6-O,O’-dimyristoyl derivative amphiphilic chitosan (DMCh), in improving the solubility of camptothecin (CPT), a hydrophobic anticancer drug, and its potential ...
Xyloglucan nano-aggregates: Physico-chemical characterisation in buffer solution and potential application as a carrier for camptothecin, an anti-cancer drug
(ELSEVIER SCI LTD, 2010)
In this work, native xyloglucan was extracted from Tamarindus indica seeds (XGT), and its properties in phosphate buffer solution (PBS) were evaluated in comparison with a commercial tamarind kernel powder (TKP). The ...
Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE
(Pergamon-Elsevier Science Ltd, 2017-12)
The transcriptional regulator FUSE Binding Protein 1 (FUBP1) is overexpressed in more than 80% of all human hepatocellular carcinomas (HCCs) and other solid tumor entities including prostate and colorectal carcinoma. FUBP1 ...
Antiproliferative activity, isolation and identification of active compound from Gaylussacia brasiliensis
(Soc Brasileira FarmacognosiaJoao PessoaBrasil, 2011)
Oxidative stress, superoxide production, and apoptosis of neutrophils in dogs with chronic kidney disease
(2013-04-01)
Oxidative stress is a key component in the immunosuppression of chronic kidney disease (CKD), and neutrophil function may be impaired by oxidative stress. To test the hypothesis that in uremic dogs with CKD, oxidative ...