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Leaves of eugenia brasiliensis used as a folk medicine contain cyclooxygenase enzyme and lipid peroxidation inhibitory compounds
(2018-01-01)
Tea prepared from leaves of Eugenia brasiliensis has been used as a folk medicine in Brazil to alleviate inflammation and pain. In this study, tea and methanolic extract inhibited cyclooxygenase (COX-1 and -2) enzymes and ...
Leaves of Eugenia brasiliensis Used as a Folk Medicine Contain Cyclooxygenase Enzyme and Lipid Peroxidation Inhibitory Compounds
(Natural Products Inc, 2018-08-01)
Tea prepared from leaves of Eugenia brasiliensis has been used as a folk medicine in Brazil to alleviate inflammation and pain. In this study, tea and methanolic extract inhibited cyclooxygenase (COX-1 and -2) enzymes and ...
Lipoperoxidation and cyclooxygenases 1 and 2 inhibitory compounds from Iryanthera juruensis
(Amer Chemical Soc, 2007-04-04)
Plants from Iryanthera genus have been traditionally used as food supplements by South American Indians. The MeOH extract of leaves of Iryanthera juruensis, one of the plants endemic to the Amazon region and consumed in ...
PROSTAGLANDIN E(2), REGULATES INDUCIBLE NITRIC-OXIDE SYNTHASE IN THE MURINE MACROPHAGE CELL-LINE J774
(Elsevier Science IncNew YorkEUA, 1995)
Anti-inflammatory intestinal activity of Arctium lappa L. (Asteraceae) in TNBS colitis model
(2013-03-07)
Ethnopharmacological relevance: In Brazilian traditional medicine, Arctium lappa (Asteraceae), has been reported to relieve gastrointestinal symptoms. Aim of the study: In the present study, we investigated the effects of ...
Lipoperoxidation and cyclooxygenase enzyme inhibitory piperidine alkaloids from Cassia spectabilis green fruits
(Amer Chemical Soc, 2007-12-01)
Phytochernical work in the search for bioactive metabolites from the methanolic extract of Senna spectabilis green fruits led to the isolation of a new piperidine alkaloid, (+)-3-O-feruloylcassine (1), in addition to the ...
The inflammatory profile of the tumor microenvironment, orchestrated by cyclooxygenase-2, promotes epithelial- mesenchymal transition
(Frontiers Media, 2021)
The tumor microenvironment (TME) corresponds to a complex and dynamic
interconnection between the extracellular matrix and malignant cells and their
surrounding stroma composed of immune and mesenchymal cells. The TME ...
Selective cyclooxygenase-2 inhibition protects against myocardial damage in experimental acute ischemia
(Faculdade de Medicina / USP, 2009)
BACKGROUND: Acute myocardial infarction is associated with tissue inflammation. Early coronary reperfusion clearly improves the outcome but may help propagate the inflammatory response and enhance tissue damage. Cyclooxygenase-2 ...
COX-2 Inhibitors for Cancer Treatment in Dogs
(Univ Agriculture, 2011-01-01)
Cancer is one of the main causes of death in canines and felines, and this fact is probably related to the increase in the longevity of these species. The longer the animals live, the higher the exposure to carcinogenic ...
COX Inhibition Profiles and Molecular Docking Studies of the Lignan Hinokinin and Some Synthetic Derivatives
(2018-01-01)
Encouraged by the anti-inflammatory activity of hinokinin in vivo, which is also observed for the analogues dinitrohinokinin and diidrocubebin, herein we used in vitro and in silico methods to assess their selectivity ...