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Biotransformation of cladribine by a magnetic immobilizated biocatalyst of Lactobacillus animalis
(Springer, 2020-07)
A stable biocatalyst with magnetic properties based on immobilized Lactobacillus animalis ATCC 35,046 to obtain 2-chloroadenine-2′-deoxyriboside, known as cladribine, is reported for the first time. This nucleoside analogue ...
Biotransformation of cladribine by a nanostabilized extremophilic biocatalyst
(Elsevier Science, 2020-11)
Cladribine (2-chloro-2′-deoxy-β-D-adenosine) is a 2′-deoxyadenosine analogue, approved by the FDA for the treatment of hairy cell leukemia and more recently has been proved for therapeutic against many autoimmune diseases ...
Múltiplas infecções oportunistas em um paciente com leucemia linfocítica crônica tratado com cladribinaSeveral opportunistic infections in a young patient with chronic lymphocytic leukemia treated with cladribine
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea, 2000)
Treatment of prolymphocytic leukemia with cladribine
(Springer VerlagNew YorkEUA, 1998)
Biotransformation of cladribine using a stabilized biocatalyst in calcium alginate beads
(American Institute of Chemical Engineers, 2019-10)
Cladribine is a nucleoside analogue widely used in the pharmaceutical industry for the treatment of several neoplasms, including hairy-cell leukemia among others. This compound has also shown efficacy in the treatment of ...
Green production of cladribine by using immobilized 2′-deoxyribosyltransferase from lactobacillus delbrueckii stabilized through a double covalent/entrapment technology
(MDPI AG, 2021-04)
Nowadays, enzyme-mediated processes offer an eco-friendly and efficient alternative to the traditional multistep and environmentally harmful chemical processes. Herein we report the enzymatic synthesis of cladribine by a ...
Cutaneous adverse reaction to 2-chlorodeoxyadenosine with histological flame figures in patients with chronic lymphocytic leukaemia
(Blackwell Publishing LtdOxfordInglaterra, 2004)
Response rate to the treatment of Waldenström macroglobulinemia: A meta-analysis of the results of clinical trials
(Elsevier Ireland Ltd, 2016)