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Astrocyte plasticity induced by emotional stress: A new partner in psychiatric physiopathology?
(Pergamon-Elsevier Science Ltd, 2016-02)
A growing body of evidence has demonstrated that astrocytes play a pivotal role in the normal functioning of the nervous system. This new conceptual framework has set the groundwork to be able to hypothesize that astrocytes ...
Tianeptine influence on plasmatic catecholamine levels and anxiety index in rats under variable chronic stress after early maternal separation
(Taylor & Francis Ltd, 2009-12)
The aim of this work was to determine the effect of chronic treatment with 5 mg/Kg of tianeptine in male adult Wistar rats separated from the mother as neonates and submitted to variable chronic stress, plasma catecholamines, ...
Maternal separation in early life modifies anxious behavior and Fos and glucocorticoid receptor expression in limbic neurons after chronic stress in rats: Effects of tianeptine.
(Taylor & Francis Ltd, 2016-01)
Early-life adversity can lead to long-term consequence persisting into adulthood. Here, we assess the implications of an adverse early environment on vulnerability to stress during adulthood. We hypothesized that the ...
Honokiol attenuates oxidative stress-dependent heart dysfunction in chronic Chagas disease by targeting AMPK / NFE2L2 / SIRT3 signaling pathway
(Elsevier Science Inc., 2020-08)
Chronic cardiomyopathyis the most serious and frequent manifestation of Chagas disease caused by Trypanosoma cruzi. Free radicals are acrucial factor in Chagas pathogenesis. Parasite infection of cardiomyocytesexacerbates ...
Differential effects of tianeptine on the dorsal hippocampal volume of rats submitted to maternal separation followed by chronic unpredictable stress in adulthood
(Taylor & Francis Ltd, 2016-11)
Early maternal separation (MS) may produce lasting effects in the dorsal hippocampus (DH) that can change its response to chronic stress in adulthood. Chronic stress affects DH morphology and function, but tianeptine (an ...
Thyroid hormone modulation of immunity: Its participation in chronic stress-induced immune alterations
(Bentham Science Publishers, 2009-10)
The interaction between the immune and the neuroendocrine systems involves, in a bidirectional circuit, shared cellular receptors and their coupled signaling pathways. Disruptions of this circuit lead to pathological ...
Perinatal Programming of Circadian Clock-Stress Crosstalk
(Hindawi Publishing Corporation, 2018-02)
An intact communication between circadian clocks and the stress system is important for maintaining physiological homeostasis under resting conditions and in response to external stimuli. There is accumulating evidence for ...
Animal models of fetal programming: Focus on chronic maternal stress during pregnancy and neurodevelopment
(Elsevier, 2017)
Animal models of fetal programming contribute in three synergistic ways to understanding and treating human diseases or predispositions to diseases, which emerge from in utero insults leading to fetal programming. Firstly, ...
Modulating offspring responses: concerted effects of stress and immunogenic challenge in the parental generation
(Company of Biologists, 2020-09)
The perception, processing and response to environmental challenges involves the activation of the immuno-neuroendocrine (INE) interplay. Concerted environmental challenges might induce trade-off when resource allocation ...
Stress-mediated hyperactivity and anhedonia resistant to diazepam and fluoxetine in Drosophila
(Taylor & Francis Ltd, 2020-05)
Distresses may induce behavioral phenotypes constituting heuristic models for psychopharmacology studies. In several species, including Drosophila, antidepressants counteract stress-induced phenotypes allowing the use of ...