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Pathophysiological role of histamine H4 Receptor in cancer: therapeutic implications
(Frontiers Media S.A., 2019-05)
Cancer is a leading cause of death in both developed and developing countries. Although advances in cancer research lead to improved anti-neoplastic therapies, they continue to have unfavorable outcomes, including poor ...
Cancer Dynamics
(Openventio Publishers, 2020-06)
Even though cancer researchers nowadays are trying to develop many key cellular pathways susceptible to be tackled by therapeutic approaches, we are far from being able to consider some cancers as curable diseases in general ...
The application of probiotics in cancer
(Cambridge University Press, 2007-10)
Lactic acid bacteria (LAB) are present in many foods such as yoghurt and are frequently used as probiotics to favour some biological functions in the host. Many investigators have evaluated the therapeutic effects of yoghurt ...
Glycans pave the way for immunotherapy in triple-negative breast cancer
(Cell Press, 2018-02)
The clinical efficacy of therapies targeting the PD-1/PD-L1 pathway is still limited. In this issue of Cancer Cell, Li and colleagues identify a PD-L1 glycosylation-based mechanism in triple-negative breast cancer that ...
An integrative model of cancer cell differentiation with immunotherapy
(IOP Publishing, 2021-10)
In order to improve cancer treatments, cancer cell differentiation and immunotherapy are the subjects of several studies in different branches of interdisciplinary sciences. In this work, we develop a new population model ...
Cancer-Associated Fibroblasts in the Breast Tumor Microenvironment
(Springer/Plenum Publishers, 2021-01)
Years of investigation have shed light on a theory in which breast tumor epithelial cells are under the effect of the stromal microenvironment. This review aims to discuss recent findings concerning the phenotypic and ...
Modern Strategies in Cancer Study: Drug Repositioning in Colorectal Cancer Treatment
(Crimson Publisher, 2019-05)
Colorectal cancer is one of the most fatal cancers in the world because most of cases are diagnosed in advanced stages, when the development of resistance to chemotherapy is more frequent. To face this situation, new drugs ...
Resultados obtenidos en las campañas de prevención de cáncer de boca David Grinspan en Mendoza Argentina desde 2014 a 2017Results obtained in the campaigns of cancer prevention of boca David Grinspan in Mendoza Argentina from 2014 to 2017
(Universidad Nacional de Cuyo. Facultad de Odontología, 2018)
Functional relationship between CFTR and RAC3 expression for maintaining cancer cell stemness in human colorectal cancer
(Springer, 2021-06)
Purpose: CFTR mutations not only cause cystic fibrosis, but also increase the risk of colorectal cancer. A putative role of CFTR in colorectal cancer patients without cystic fibrosis has so far, however, not been investigated. ...
Drug-based cancer therapy to overcome immune resistance by steering tumor evolution
(Informa Healthcare, 2019-01)
We argue that therapy must lead rather than follow vis-à-vis cancer evolution. Clinical experience suggests that the evading phenotype resulting from treatment can never be fully anticipated or eliminated when a single ...