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Comment on "Genetic variants and source of introduction of SARS-CoV-2 in South America"
(Wiley, 2020)
I read with great interest a recent study by Poterico and Mestanza who described mutations in 30 SARS‐CoV‐2 genomes from South American countries (Argentina, Brazil, Chile, Colombia, Ecuador, and Peru). Next‐generation ...
Progesterone regulates the expression and activity of two mouse isoforms of the glycoprotein folding sensor UDP-Glc: Glycoprotein glucosyltransferase (UGGT)
(Elsevier Science, 2013-12)
UDP-Glucose:glycoprotein glucosyltransferase (UGGT) is a central component of the endoplasmic reticulum (ER) glycoprotein-folding quality control system, which prevents the exit of partially folded species. UGGT activity ...
Membrane localization of Junín virus glycoproteins requires cholesterol and cholesterol rich membranes
(Academic Press Inc Elsevier Science, 2013-01)
Arenavirus morphogenesis and budding occurs at cellular plasma membrane;however, the nature of membrane assembly sites remains poorly understood. In this study we examined the effect of different cholesterol-lowering ...
The ER glycoprotein folding sensor UDP-Glc: glycoprotein glucosyltransferase is broadly expressed in C. elegans hermaphrodite
(Caltech Library, 2020-08)
The endoplasmic reticulum (ER) uses an elaborate system called the ER quality control (QC) to monitor the proper folding of newly synthesized glycoproteins. The QC allows cells to differentiate between properly folded and ...
Replacement of the V3 Domain in the Surface Subunit of the Feline Immunodeficiency Virus Envelope Glycoprotein with the Equivalent Region of a T Cell-Tropic Human Immunodeficiency Virus Type 1 Results in a Chimeric Surface Protein That Efficiently Binds to CXCR4
(Mary Ann Liebert, 2014-03)
Feline immunodeficiency virus (FIV) and the T cell-tropic strains of human immunodeficiency virus type 1 (HIV-1) share the use of the chemokine receptor CXCR4 for cell entry. To study this process further we developed a ...
Improving bioreactor production of a recombinant glycoprotein in Escherichia coli: Effect of specific growth rate on protein glycosylation and specific productivity
(John Wiley & Sons Inc, 2019-02)
In the last decades bacterial glycoengineering emerged as a new field as the result of the ability to transfer the Campylobacter jejuni N- glycosylation machinery into Escherichia coli for the production of recombinant ...
Origin and Evolution of Two Independently Duplicated Genes Encoding UDP- Glucose: Glycoprotein Glucosyltransferases in Caenorhabditis and Vertebrates
(Genetics Society of America, 2019-12)
UDP- glucose: glycoprotein glucosyltransferase (UGGT) is a protein that operates as the gatekeeper for the endoplasmic reticulum (ER) quality control mechanism of glycoprotein folding. It is known that vertebrates and ...
Detection and quantification of anti-rabies glycoprotein antibodies: current state and perspectives
(Springer, 2021-09)
Rabies is an ancient fatal disease with no other available treatment than post-exposure vaccination, where the bite of infected animals, mainly dogs, is the leading cause of its transmission to human beings. In this context, ...
The cloning of the virus envelope glycoprotein F of canine distemper virus expressed in Pichia pastoris
(Academic Press Ltd - Elsevier Science Ltd, 2020-05)
Canine distemper virus (CDV) is a pathogen which affects members of the Canidae family, causing an acute, often fatal, systemic disease. CDV is an RNA virus of the family Paramyxoviridae that contains two envelope ...