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Mostrando ítems 21-30 de 47
Expresión de BACE-1 y su asociación con astrogliosis y taupatía en demencias
(Grupo de Neurociencias de AntioquiaEl Carmen de Viboral, Colombia, 2020)
Lipoprotein receptors, cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer’s disease
(2009)
Amyloid-beta (Abeta) peptide accumulation in the brain is central to the pathogenesis of Alzheimer's disease (AD). Abeta is produced through proteolytic processing of a transmembrane protein, beta-amyloid precursor protein ...
Is it All Said for NSAIDs in Alzheimer's Disease? Role of Mitochondrial Calcium Uptake
(Bentham Science Publishers, 2018-04)
Epidemiological data suggest that non-steroidal anti-inflammatory drugs (NSAIDs) may protect against Alzheimer´s disease (AD). Unfortunately, recent trials have failed in providing compelling evidence of neuroprotection. ...
Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations
(BioMed Central, 2008-11)
BACKGROUND: Mutations in the presenilin (PSEN) genes are associated with early-onset familial Alzheimer's disease (FAD). Biochemical characterizations and comparisons have revealed that many PSEN mutations alter ...
Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein
(Academic Press Ltd Elsevier Science LtdLondonInglaterra, 2006)
Ação da Quinacrina, inibidor de PLA2, sobre a proteína beta-amiloide em modelo de Doença de Alzheimer em Drosophila melanogasterAction of Quinacrine, PLA2 inhibitor, on beta-amyloid protein in a model of Alzheimer's Disease in Drosophila melanogaster
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Genética e Bioquímica, 2020)