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Modulation of monocrotaline-induced cor pulmonale by grape juice
(Lippincott Williams, 2010-01)
The study was designed to test whether the ingestion grape juice (GJ) could modulate monocrotaline (MCT)-induced Cor pulmonale resulting from antioxidant properties. Three-week-old male Wistar rats received GJ (10 mL/kg/day) ...
Oxidative stress and altered steroidogenesis in the ovary by cholinergic stimulation of coeliac ganglion in the first proestrous in rats. Implication of nitric oxide
(Academic Press Inc Elsevier Science, 2016-02-29)
An ex-vivo Coeliac Ganglion-Superior Ovarian Nerve-Ovary (CG-SON-O) system from virgin rats in the first proestrous was used to test whether cholinergic stimulation of CG affects oxidative status and steroidogenesis in the ...
Metabotropic glutamate receptor 3 activation prevents nitric oxide induced death in cultured astrocytes
(Wiley, 2009-12)
Altered glial function may contribute to the initiation or progression of neuronal death in neurodegenerative diseases. Thus, modulation of astrocyte death may be essential for preventing pathological processes in the CNS. ...
Thyroid hormones increase inducible nitric oxide synthase gene expression down-stream PKC Đ in murine tumor T lymphocytes.
(American Physiological Society, 2006-02-22)
Regulation of cell proliferation by thyroid hormone (TH) has been demonstrated, but the effect of THs and the mechanisms involved in lymphocyte activity have not been elucidated. Differential expression of PKC isoenzymes ...
Structure-actvity relationship of nitric oxide synthase inhibitors: a theoretical approach
(C M B Association, 2002)
Crambescin C1 Acts as A Possible Substrate of iNOS and eNOS Increasing Nitric Oxide Production and Inducing In Vivo Hypotensive Effect
(Frontiers Media, 2021-07)
Crambescins are guanidine alkaloids from the sponge Crambe crambe. Crambescin C1 (CC) induces metallothionein genes and nitric oxide (NO) is one of the triggers. We studied and compared the in vitro, in vivo, and in silico ...
Signal transduction pathways involved in non-genomic action of estrone on vascular tissue
(Elsevier Science Inc, 2006-10)
Previously we demonstrated that estrone non-genomically regulates rat aortic NOS and COX activity and that this effect depends on ovarian activity. The purpose of the present study was to characterize this effect and ...
Cytoprotective role of nitric oxide associated with Hsp70 expression in neonatal obstructive nephropathy
(Academic Press Inc Elsevier Science, 2008-12)
Nitric oxide (NO) has emerged as an important endogenous inhibitor of apoptosis. In this study, we postulated that the mechanism of apoptosis inhibition by NO would include stimulation of heat shock protein 70 (Hsp70) ...
Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: Arginase I is expressed in infiltrating CD68+ macrophages
(University of Chicago Press, 2008-06)
In Chagas disease, which is caused by Trypanosoma cruzi, macrophages and cardiomyocytes are the main targets of infection. Classical activation of macrophages during infection is protective, whereas alternative activation ...
N-nitrosomelatonin enhances photic synchronization of mammalian circadian rhythms
(Wiley, 2013-12)
Most physiological processes in mammals are synchronized to the daily light:dark cycle by a circadian clock located in the hypothalamic suprachiasmatic nucleus. Signal transduction of light-induced phase advances of the ...