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Metformin promotes autophagy in Echinococcus granulosus larval stage
(Elsevier Science, 2018-09)
Cystic echinococcosis is a neglected parasitic disease caused by the larval stage of Echinococcus granulosus for which an effective treatment is not yet available. Since autophagy constitutes a homeostatic mechanism during ...
Exogenous ketone bodies ameliorate behavioral defects associated with DAF-18/PTEN mutations
(Instituto de Biología de Rosario, 2020)
The phosphatidylinositol 3-kinase (PI3K) signaling pathway is a conserved signal transduction cascade involved in several processes, including neurodevelopment. The lipid phosphatase DAF-18/PTEN inhibits the PI3K signaling ...
Metabolic stress-induced activation of foxo1 triggers diabetic cardiomyopathy in miceJOURNAL OF CLINICAL INVESTIGATIONJ CLIN INVEST
(AMER SOC CLINICAL INVESTIGATION INC, 2016)