Articulo
FoxO1 mediates TGF-beta1-dependent cardiac myofibroblast differentiation
Biochim Biophys Acta
Registro en:
15130011
15130011
Autor
Vivar, R.
Humeres, C.
Muñoz, C.
Boza, P.
Bolivar, S.
Tapia, F.
Lavandero, S.
Chiong, M.
Diaz-Araya, G.
Institución
Resumen
Cardiac fibroblast differentiation to myofibroblast is a crucial process in the development of cardiac fibrosis and is tightly dependent on transforming growth factor beta-1 (TGF-β1). The transcription factor forkhead box O1 (FoxO1) regulates many cell fu FONDAP FONDAP