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New insights in novel Escherichia coli colistin resistant strains isolated from Argentina
(Springer, 2020-05)
Colistin is a polymyxin antibiotic (polymyxin E) that has in recent years re-emerged as an option for treatment of multidrug-resistant bacteria. Recently, the re-introduction of colistin resulted in the appearance of ...
Influence of carbonyl groups on the interaction of PLA2 with lipid interphases
(Elsevier, 2020-11)
It is known that phospholipase A2 (PLA2) hydrolyzes phosphatidylcholines (PC) producing lysophosphatidylcholine and fatty acids. The substrate of the enzymatic action is the sn2 acyl chain being Ca2+ ion an essential ...
Antiradical activity of gallic acid included in lipid interphases
(Elsevier, 2014-04)
Polyphenols are well known as antioxidant agents and by their effects on the hydration layers of lipid interphases. Among them, gallic acid and its derivatives are able to decrease the dipole potential and to act in water ...
Volume recovery, surface properties and membrane integrity of Lactobacillus delbrueckii subsp. bulgaricus dehydrated in the presence of trehalose or sucrose
(Wiley Blackwell Publishing, Inc, 2007-07)
Aims: Although the practical importance of adding sugars before drying is well known, the mechanism of protection of bacteria by sugars is not clear. The response of the dehydrated micro-organisms to rehydration is analysed ...
First steps in the formulation of praziquantel nanosuspensions for pharmaceutical applications
(Taylor & Francis, 2020-08)
Praziquantel (PZQ), a broad spectrum anthelmintic drug, cannot be found in acceptable dosage forms for elderly patients, paediatric patients, and for veterinary use. In fact, very little has been done up to now in the ...
Processing of concentrated aqueous zirconia-bioglass slips by slip casting
(Inst Chemical Technology, 2017-02)
3 mol% yttria-partially stabilized zirconia (Y-TZP) powder and a sol-gel derived CaO- P₂O₅- SiO₂ (64S) bioglass, were used to produce Y-TZP- bioglass slip cast compacts. The rheological properties of concentrated aqueous ...
Interaction of hydroxy-xanthones with phosphatidylcholines: The effector decreases compressibility and increases the fluidity of membranes
(Elsevier Science, 2020-09)
This work reports the effect of hydroxy-xanthones (XAs) on 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine(DPPC) and 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) bilayers as determined by ultrasound velocimetry,densimetry ...
Pros and cons of coating layered double hydroxide nanoparticles with polyacrylate
(Elsevier Science, 2019-05)
Preventing the aggregation of layered double hydroxide nanoparticles (LDH-NP) and producing additional functionality are two important objectives for their applications as drug nanocarriers, among others. Adsorption of ...
Unravelling the mechanism of action of “de novo” designed peptide P1 with model membranes and gram-positive and gram-negative bacteria
(Elsevier Science Inc., 2020-10)
In the last years, the decreasing effectiveness of conventional antimicrobial-drugs has caused serious problems due to the rapid emergence of multidrug-resistant pathogens. This situation has brought attention to other ...
Use of organo-montmorillonite for the nitrate retention in water: Influence of alkyl length of loaded surfactants
(Springer Nature, 2019-10-03)
The removal of NO3− from water was performed and compared among four organo-montmorillonites (OMt) with quaternary amine surfactants of different chain lengths [octadecyl trimethyl-(ODTMA), hexadecyl trimethyl-(HDTMA), ...