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Leptin promotes cell proliferation and survival of trophoblastic cells
(Society for the Study of Reproduction, 2007-02)
Leptin, the 16-kDa protein product of the obese gene, was originally considered as an adipocyte-derived signaling molecule for the central control of metabolism. However, leptin has been suggested to be involved in other ...
Molecular mechanisms underlying progesterone receptor action in breast cancer: Insights into cell proliferation and stem cell regulation
(Elsevier Science Inc, 2019-12)
The ovarian steroid hormone progesterone and its nuclear receptor, the Progesterone Receptor (PR), play an essential role in the regulation of cell proliferation and differentiation in the mammary gland. In addition, ...
Postnatal metformin treatment alters rat Sertoli cell proliferation and daily sperm production
(Blackwell Publishing Ltd, 2021-05)
The direct correlation between Sertoli cell number and sperm production capacity highlights the importance of deciphering external factors that modify Sertoli cell proliferation. A growing body of evidence in vitro suggests ...
Apoptotic and proliferating hepatocytes differ in prothymosin alpha expression and cell localization
(Springer, 2006-10)
Prothymosin alpha is an acidic protein, reported to be involved in cell proliferation and apoptosis, although its precise function in both processes are still unknown. Due to the importance of these processes in the ...
Repression of Growth Regulating Factors by the MicroRNA396 Inhibits Cell Proliferation by UV-B Radiation in Arabidopsis Leaves
(American Society of Plant Biologist, 2013-09)
Because of their sessile lifestyle, plants are continuously exposed to solar UV-B radiation. Inhibition of leaf growth is one of the most consistent responses of plants upon exposure to UV-B radiation. In this work, we ...
Involvement of KLF14 and egr-1 in the TGF-beta1 action on Leydig cell proliferation
(Academic Press Ltd - Elsevier Science Ltd, 2013-02)
Transforming growth factor β1 (TGF-β1) is a pleiotropic cytokine that modulates cell homeostasis. In Leydig cells, TGF-β1 exerts stimulatory and inhibitory effect depending on the type I receptor involved in the signaling ...
Cell proliferation and survival mechanisms underlying the abnormal persistence of follicular cysts in bovines with cystic ovarian disease induced by ACTH
(Elsevier Science, 2010-10)
Cystic ovarian disease (COD) is an important cause of infertility that affects cattle. Alterations in the ovarian micro-environment of females with follicular cysts could alter the normal processes of proliferation and ...
The role of zinc in the modulation of neuronal proliferation and apoptosis
(Springer, 2010-01)
Although a requirement of zinc (Zn) for normal brain development is well documented, the extent to which Zn can modulate neuronal proliferation and apoptosis is not clear. Thus, we investigated the role of Zn in the ...
Citrus reticulata peel oil inhibits non-small cell lung cancer cell proliferation in culture and implanted in nude mice
(Royal Society of Chemistry, 2018-04)
Non-small cell lung cancer (NSCLC) accounts for most cases of lung cancer. The peel oil of Mandarin Citrus reticulata Blanco cv. Dancy (MPO) is a natural source of essential oils and carotenoids. Volatile and non-volatile ...
Geraniol inhibits tumor cell proliferation in vitro and in vivo by posttranscriptional regulation of HMGCR
(Palacky Univ, 2012-07)
Plant isoprenoids are widely known as nontoxic natural compounds that inhibit cell proliferation with selectivity against tumor cells. Isoprenoids are also potent suppressors of the 3-hydroxy-3-methylglutaryl coenzyme A ...