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GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment
(American Association for the Advancement of Science, 2014-09)
The lateral habenula (LHb), a key regulator of monoaminergic brain regions, is activated by negatively valenced events. Its hyperactivity is associated with depression. Although enhanced excitatory input to the LHb ...
Encapsulation of florfenicol by in situ crystallization into novel alginate-Eudragit RS® blended matrix for pH modulated release
(Editions Sante, 2019-12)
Florfenicol (FF) is a broad-spectrum antibiotic with the drawback of poor solubility in physiological media. Despite vehiculization of FF become an alternative, current devices usually showed low encapsulation efficiencies(EE) ...
In situ Formed Implants, Based on PLGA and Eudragit Blends, for Novel Florfenicol Controlled Release Formulations
(John Wiley & Sons Inc, 2020-11)
Drug controlled release technologies (DCRTs) represent an opportunity for designing new therapies. Main objectives are dose number optimization and secondary effects reduction to improve the level of patient/client acceptance. ...
Preparation and characterization of lignin microparticles-in-alginate beads for atrazine controlled release
(Springer/Plenum Publishers, 2019-09)
The use of lignin as polymeric matrices for controlled release systems in agriculture is a promising alternative for its revalorization. In this work, different atrazine delivery systems were studied. Lignin derived from ...
Flavor release by enzymatic hydrolysis of starch samples containing vanillin-amylose inclusion complexes
(Elsevier Science, 2014-05)
Hylon VII is a high amylose corn starch which has excellent gelling properties, and its behavior as flavor encapsulant is relevant to the food industry because its ability to regulate a swelling-controlled release in aqueous ...
Controlled release of micronutrients from surface-modified polymer films for agricultural applications
(Springer, 2021-05)
Active polyethylene/carbon black films with the capability of controlled release of micronutrients were developed in this work. A simple technique allowed modifying film surface through the incorporation of different mineral ...
Validation of kinetic modeling of progesterone release from polymeric membranes
(Shenyang Pharmaceutical University, 2018-01)
Mathematical modeling in drug release systems is fundamental in development and optimization of these systems, since it allows to predict drug release rates and to elucidate the physical transport mechanisms involved. In ...
Participation of the GABAergic system on the glutamate release of frontal cortex synaptosomes from Wistar rats with experimental autoimmune encephalomyelitis
(Pergamon-Elsevier Science Ltd, 2011-08)
We previously found that the glutamate release was decreased in synaptosomes from rat cerebral cortex during the development of experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis. Various ...
The effect of D-aspartate on luteinizing hormone-releasing hormone, α-melanocyte-stimulating hormone, GABA and dopamine release
(Lippincott Williams, 2002-12)
Since D-aspartate stimulates prolactin and LH release, our objective was to determine whether D-aspartate modifies the release of hypothalamic and posterior pituitary factors involved in the control of their secretion and ...