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Metabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells
(American Physiological Society, 2014-07)
PNPLA3 was recently associated with the susceptibility to nonalcoholic fatty liver disease, a common cause of chronic liver disease characterized by abnormal triglyceride accumulation. Although it is established that PNPLA3 ...
Efficient method for targeted gene disruption by homologous recombination in Mycobacterium avium subspecie paratuberculosis
(Elsevier Science, 2020-04)
Targeted gene disruption by homologous recombination, has been widely used in mycobacterium species to understand the genetic basis of virulence and persistence in the host and to develop efficacious potential live vaccines. ...
Functional milk fat enriched in conjugated linoleic acid prevented liver lipid accumulation induced by a high-fat diet in male rats
(Royal Society of Chemistry, 2021-06)
The aim was to investigate the potential effect of functional milk fat (FMF), naturally enriched in conjugated linoleic acid, on the prevention of liver lipid accumulation and some biochemical mechanisms involved in the ...
Lipid metabolism alterations in the neuronal response to A53T α-synuclein and Fe-induced injury
(Elsevier Science Inc, 2018-10-08)
Pathological α-synuclein (α-syn) overexpression and iron (Fe)-induced oxidative stress (OS) are involved in the death of dopaminergic neurons in Parkinson's disease (PD). We have previously characterized the role of ...
Nutritional and metabolic effects of dietary trans fats depend on the intake of linoleic acid
(Wiley VCH Verlag, 2015-07)
This study aimed to investigate the differential effects of trans fatty acids (TFA) on the nutritional parameters, serum and tissue triacylglycerol (TAG) levels, as well as the mechanisms involved in their regulation, in ...
Insights into the metabolism of oleaginous Rhodococcus spp
(American Society for Microbiology, 2019-07)
Some species belonging to the Rhodococcus genus, such as Rhodococcus opacus, R. jostii, and R. wratislaviensis, are known to be oleaginous microorganisms, since they are able to accumulate triacylglycerols (TAG) at more ...
Lipid storage in high-altitude Andean Lakes extremophiles and its mobilization under stress conditions in Rhodococcus sp. A5, a UV-resistant actinobacterium
(Springer Tokyo, 2013-03)
The production of triacylglycerols (TAG) or wax esters (WS) seems to be a widespread feature among extremophile bacteria living in high-altitude Andean Lakes (HAAL), Argentina. Twelve out of twenty bacterial strains isolated ...
Lipid and fatty acid composition of canine lipoproteins
(Elsevier Science Inc, 2001-04)
Lipid classes and their fatty acids were studied in the major lipoprotein fractions from canine, in comparison with human, plasma. In dogs, high-density-lipoprotein (HDL), the main carrier of plasma phospholipid (PL), ...
Bio-paraffin from Soybean Oil as Eco-friendly Alternative to Mineral Waxes
(American Chemical Society, 2021-04)
Blends of fully and partial hydrogenated soybean oil, with 50/50 and 80/20 wt %, were chemically interesterified. The composition-texture relationships were investigated and established for the set of investigated materials. ...
Whey as a renewable source for lipid production by Rhodococcus strains: Physiology and genomics of lactose and galactose utilization
(Wiley VCH Verlag, 2016-02)
We investigated biomass and lipid production from whey by different Rhodococcus strains. The studied microorganisms exhibited different capability for growing and producing lipids from whey permeate. Strains belonging to ...