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Novel pteridine alkaloids from the sponge Clathria sp.
(Pergamon-Elsevier Science Ltd, 2002-05)
Three novel pteridine alkaloids, pseudoanchynazines A-C (1-3) have been isolated from the sponge Clathria sp. collected by trawling (-100m) in a commercial clam fishery near the coasts of Rio Negro, Argentina, and their ...
Degradation of alfa-melanocyte-stimulating hormone photosensitized by pterin
(Royal Society of Chemistry, 2014-04)
Oxidized pterins, efficient photosensitizers under UV-A irradiation, accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder. In this work, we have investigated the ability of pterin ...
Interactions between imazethapyr and bovine serum albumin: Spectrofluorimetric study
(Elsevier Science, 2012-10)
The interaction between imazethapyr (IMA) and bovine serum albumin (BSA) was investigated by fluorescence spectroscopy. The Stern-Volmer quenching constant (K SV) at three temperatures was evaluated in order to determine ...
Scavengers protection of cells against ALA-based photodynamic therapy-induced damage
(Springer London Ltd, 2002-10)
The exogenously stimulated formation of intracellularly generated protoporphyrin IX, a precursor of haem, is becoming one of the fastest developing areas in the field of photodynamic therapy (PDT). We tested the action of ...
Structural Study of a Flexible Active Site Loop in Human Indoleamine 2,3-Dioxygenase and Its Functional Implications
(American Chemical Society, 2016-05)
Human indoleamine 2,3-dioxygenase catalyzes the oxidative cleavage of tryptophan to N-formyl kynurenine, the initial and rate-limiting step in the kynurenine pathway. Additionally, this enzyme has been identified as a ...
UV Resistance and Photoreactivation of Extremophiles from High-Altitude Andean Lakes
(Elsevier, 2013-04)
He HAAL are natural laboratories for exploring and monitoring in situ interactions between the geophysical environment and the dynamics of biodiversity. Solar irradiation (including high UV-B doses) is without doubt the ...
Triplet state quenching of phenosafranine dye by indolic compounds studied by transient absorption spectroscopy
(Royal Society of Chemistry, 2015-02)
The interaction of the triplet state of the synthetic dye phenosafranine (3,7-diamino-5-phenylphenazinium chloride) with indolic compounds of biological relevance was investigated in water by means of laser flash photolysis. ...
UVR8 mediates UV-B-induced Arabidopsis defense responses against Botrytis cinerea by controlling sinapate accumulation
(Elsevier, 2012-05)
Light is emerging as a central regulator of plant immune responses against herbivores and pathogens. Solar UV-B radiation plays an important role as a positive modulator of plant defense. However, since UV-B photons can ...
The photodynamic activity of a novel porphyrin derivative bearing a fluconazole structure in different media and against Candida albicans
(Elsevier, 2010-11)
The spectroscopic properties and photodynamic activity of a novel porphyrin covalently linked to an antifungal fluconazole structure were investigated in DMF and different biomimetic systems, results being compared with ...
ROS-generating rare-earth coordination networks for photodynamic inactivation of Candida albicans
(Royal Society of Chemistry, 2021-03-31)
Water–ethanol suspensions of 2D coordination network (CN) based on rare earth elements and mixed ligands were evaluated as reactive oxygen species (ROS) generators under UV light irradiation, in contact with a biomimetic ...