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Mostrando ítems 81-90 de 96
Membrane anchoring stabilizes and favors secretion of New Delhi metallo-β-lactamase
(Nature Publishing Group, 2016-07)
Carbapenems, 'last-resort' β-lactam antibiotics, are inactivated by zinc-dependent metallo-β-lactamases (MBLs). The host innate immune response withholds nutrient metal ions from microbial pathogens by releasing metal-chelating ...
Occurrence of plasmidic AmpC β-lactamase in a Salmonella Typhimurium isolate of equine origin: First report of CMY-2 in animals in Argentina
(Elsevier, 2015-12)
The increase in transferable resistance to third-generation cephalosporins in zoonotic Salmonella constitutes a serious public health threat. Resistance to third-generation cephalosporins is mainly due to acquisition of ...
Molecular characterization of a clinical Haemophilus parainfluenzae isolate with cefotaxime resistance and decreased susceptibility to fluoroquinolones
(Elsevier Science, 2016-10)
We report an H. parainfluenzae clinical isolate resistant to cefotaxime and with decreased susceptibility to ciprofloxacinrecovered from a patient with cystic fibrosis. The isolate had elevated MICs of ampicillin (256 ...
Outbreak of a Cluster with Epidemic Behavior due to Serratia marcescens after colistin administration in a hospital setting
(American Society for Microbiology, 2013-07)
Serratia marcescens causes health care-associated infections with important morbidity and mortality. Particularly, outbreaks produced by multidrug-resistant isolates of this species, which is already naturally resistant ...
Mujeres y trabajos en el siglo XXI: una aproximación desde datos secundariosWomen and works in the 21st century: an approach from statistical data
(Universidade Federal de Pelotas. Programa de Pós-Graduação em Sociologia, 2020-07)
En este artículo contextualizamos el mundo del trabajo a partir de la descripción de variables sociodemográficas provenientes de datos secundarios disponibles para una ciudad del interior de Argentina. Dicho propósito se ...
MALDI-TOF MS based procedure to detect KPC-2 directly from positive blood culture bottles and colonies.
(Elsevier Science, 2019-04)
In this study, we identified specific carbapenemase-producing isolates applying an easy and rapid protocol for the detection of mature KPC-2 β-lactamase by MALDI-TOF MS from colony and positive blood culture bottles. In ...
Acinetobacter baumannii NCIMB8209: A rare environmental strain displaying extensive insertion sequence-mediated genome remodeling resulting in the loss of exposed cell structures and defensive mechanisms
(American Society for Microbiology, 2020-07)
Acinetobacter baumannii represents nowadays an important nosocomial pathogen of poorly defined reservoirs outside the clinical setting. Here, we conducted whole-genome sequencing analysis of the Acinetobacter sp. NCIMB8209 ...
Two recombinant human interferon-beta 1a pharmaceutical preparations produce a similar transcriptional response determined using whole genome microarray analysis
(Dustri-Verlag Dr. Karl Feistle, 2008-02)
Objectives: Recombinant human interferon-beta (IFN-b) is a well-established treatment for multiple sclerosis (MS). The regulatory process for marketing authorization of biosimilars is currently under debate in certain ...
B-lactamase remodeling and evolution of collateral resistance in hypermutator Pseudomonas aeruginosa upon long-term antibiotic therapy
(Cold Spring Harbor, 2021-05)
Bacteria are endowed with a unique ability to adapt to challenging environments. The evolution of bacterial populations during chronic infections involves a large diversity of adaptive mechanisms that cannot always be ...