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Interaction of p53 with tumor suppressive and oncogenic signaling pathways to control cellular reactive oxygen species production
(Mary Ann Liebert, 2011-09)
p53 is a crucial transcription factor with tumor suppressive properties that elicits its function through specific target genes. It constitutes a pivotal system that integrates information received by many signaling pathways ...
Characterisation and reactivity continuum of dissolved organic matter in forested headwater catchments of Andean Patagonia
(Wiley, 2018-09)
Terrestrial inputs of dissolved organic matter (DOM) make a significant contribution to the carbon pool of headwaters and the reactivity of this pool depends on its source and diagenetic state, being influenced by photochemical ...
Effect of aerial exposure on the antioxidant status in the subantarctic stone crab Paralomis granulosa (Decapoda: Anomura)
(Elsevier Science Inc., 2007-07)
In Tierra del Fuego (Southern South America), the stone or false king crab, Paralomis granulosa represents one of the most important crabfisheries. After capture, animals are kept in baskets and exposed to dryness for ...
Ultra-low concentration protein detection based on phenylalanine-Pd/SWCNT as a high sensitivity nanoreceptor
(Royal Society of Chemistry, 2020-01-14)
Pd doped single-walled carbon nanotubes as an enhanced physical transducer with phenylalanine amino acid can be efficiently used as a biocompatible nanoreceptor to detect proteins. DFT/B3LYP was used to calculate the ...
Partial Reversal of Striatal Damage by Palmitoylethanolamide Administration Following Perinatal Asphyxia
(Frontiers Media S.A., 2020-01)
Perinatal asphyxia (PA) is a clinical condition brought by a birth temporary oxygen deprivation associated with long-term damage in the corpus striatum, one of the most compromised brain areas. Palmitoylethanolamide (PEA) ...
Genetic and subunit vaccines based on the stem domain of the equine influenza hemagglutinin provide homosubtypic protection against heterologous strains
(Elsevier, 2018-03-14)
H3N8 influenza virus strains have been associated with infectious disease in equine populations throughout the world. Although current vaccines for equine influenza stimulate a protective humoral immune response against ...
Requirement for BDNF in the reconsolidation of fear extinction
(Society for Neuroscience, 2015-04)
Therapies based on the impairment of reconsolidation or the enhancement of extinction offer the possibility of decreasing the persistent recollection of distressing memories. However, the direct interplay between reconsolidation ...
Production of white, red and black quinoa (Chenopodium quinoa willd var. real) protein isolates and its hydrolysates in germinated and non-germinated quinoa samples and antioxidant activity evaluation
(Multidisciplinary Digital Publishing Institute, 2019-07-30)
Red, black and white seeds quinoa were germinated at 28◦ C during 24 (G1), 48 and 72 h (G3). Red quinoa presented a higher percentage of germination with a value of 46% of germination at 72 h. Quinoa protein isolate (QPI) ...
Pectin-Coated Plasmonic Nanoparticles for Photodynamic Therapy: Inspecting the Role of Serum Proteins
(American Chemical Society, 2021-05)
Plasmonic metal nanoparticles (NPs) can be used as enhancers of the efficiency of standard photosensitizers (PSs) in photodynamic therapy (PDT). Protein corona, the adsorption layer that forms spontaneously around NPs once ...
Recombinant heat shock protein 27 (HSP27/HSPB1) protects against cadmium-induced oxidative stress and toxicity in human cervical cancer cells
(Springer, 2017-05)
Cadmium (Cd) is a carcinogen with several welldescribed toxicological effects in humans, but its molecular mechanisms are still not fully understood. Overexpression of heat shock protein 27 (HSP27/HSPB1)—a multifunctional ...