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The kinin B-1 receptor regulates muscle-specific E3 ligases expression and is involved in skeletal muscle mass control
(Portland Press Ltd, 2014-08-01)
Regulation of muscle mass depends on the balance between synthesis and degradation of proteins, which is under the-control of different signalling pathways regulated by hormonal, neural and nutritional stimuli. Such stimuli ...
The Role of Kinin Receptors in Preventing Neuroinflammation and Its Clinical Severity during Experimental Autoimmune Encephalomyelitis in Mice
(Public Library Science, 2011-11-22)
Background: Multiple sclerosis (MS) is a demyelinating and neuroinflammatory disease of the human central nervous system (CNS). the expression of kinins is increased in MS patients, but the underlying mechanisms by which ...
Kinin B(2) receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice
(Biomed Central Ltd, 2008-11-05)
Background: Kinins are important mediators of inflammation and act through stimulation of two receptor subtypes, B(1) and B(2). Leukocyte infiltration contributes to the pathogenesis of autoimmune inflammation in the central ...
Late auditory event-related evoked potential (P300) in Down's syndrome patients
(Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, 2010-03-01)
Down syndrome is caused by a trisomy of chromosome 21 and is associated with central auditory processing deficit, learning disability and, probably, early-onset Alzheimer's disease. Aim: to evaluate the latencies and ...
Foetal echoencephalography and Doppler ultrasonography of the middle cerebral artery in canine foetuses
(2013-03-01)
Objectives: This study aimed to evaluate the characteristics of the brain and vascular indicesof the middle cerebral artery of canine foetuses. Methods: Twenty-five bitches were selected. Tissue development, echogenicity, ...
Imipramine reverses depressive-like parameters in pneumococcal meningitis survivor rats
(Journal of Neural Transmission, 2018)
First detection of Leishmania infantum DNA within the brain of naturally infected dogs
(Elsevier B.V., 2015)
Modulatory effects of tuberculosis vaccines on experimental autoimmune encephalomyelitis
(Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP), 2009-01-01)
Although BCG is the only accepted vaccine against tuberculosis (TB), its protective ability is very limited. Therefore, many new vaccines are being evaluated. Our group has been working on DNAhsp65 - a genetic construction ...