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Lysine acetylation as drug target in fungi: an underexplored potential in Aspergillus spp.
(SBM, 2020)
In recent years, the intensification of the use of immunosuppressive therapies has increased the incidence of invasive infections caused by opportunistic fungi. Considering that, the spread of azole resistance and amphotericin ...
Regional differences in the management and outcome of kidney transplantation in patients with human immunodeficiency virus infection: A 3-year retrospective cohort study
(Wiley, 2017)
Background: In the developed world, kidney transplantation (KT) in patients with human immunodeficiency virus (HIV) infection is well established. Developing countries concentrate 90% of the people living with HIV, but ...
Comparative histopathology of endomyocardial biopsies in chagasic and non-chagasic heart transplant recipients
(Elsevier B.V., 2001-05-01)
Background: Heart transplantation has been an option for the treatment of chagasic (C) cardiomyopathy despite difficulties concerning the control of rejection and reactivation. The parasite-host interaction under the ...
Epidemiologia do carcinoma basocelular
(Sociedade Brasileira de Dermatologia, 2011-04-01)
O carcinoma basocelular é a neoplasia maligna mais comum em humanos e sua incidência vem aumentando nas últimas décadas. Sua grande frequência gera significativo ônus ao sistema de saúde, configurando problema de saúde ...
Recent mouse and rat methods for the study of experimental oral candidiasis
(2013-07-17)
The Candida genus expresses virulence factors that, when combined with immunosuppression and other risk factors, can cause different manifestations of oral candidiasis. The treatment of mucosal infections caused by Candida ...
Surgical treatment of type I neuritis in a teenage boy with borderline tuberculoid leprosy
(Soc Brasileira Medicina Tropical, 2015)
Imatinib mesylate alters the expression of genes related to disease progression in an animal model of uveal melanoma
(Ios Press, 2011-01-01)
Imatinib mesylate (IM) is a compound that inhibits both BCR-ABL tyrosine kinase and c-kit receptors. Tyrosine kinases are important in cellular signaling and mediate major cellular processes such as proliferation, ...
Mortality Profile Related to Systemic Lupus Erythematosus: A Multiple Cause-of-death Analysis
(J Rheumatol Publ Co, 2012-03-01)
Objective. To analyze the mortality profile related to systemic lupus erythematosus (SLE) in the state of São Paulo, Brazil.Methods. for the 1985-2007 period, we analyzed all death certificates (n = 4815) on which SLE was ...
Vaccine antibodies and T- and B-cell interaction in juvenile systemic lupus erythematosus
(Sage Publications Ltd, 2011-06-01)
Both systemic lupus erythematosus (SLE) and its treatment can cause immunosuppression and a decreased response to vaccination. We evaluated 30 children and adolescents with SLE, and 14 age-matched healthy subjects (control ...