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ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways
(2021-02-03)
The SARS-CoV-2 pandemic of 2020 has mobilised scientists around the globe to research all aspects of the coronavirus virus and its infection. For fruitful and rapid investigation of viral pathomechanisms, a collaborative ...
Intrinsic Feedbacks in MAPK Signaling Cascades Lead to Bistability and Oscillations
(Springer, 2013-02)
Previous studies have demonstrated that double phosphorylation of a protein can lead to bistability if some conditions are fulfilled. It was also shown that the signaling behavior of a covalent modification cycle can be ...
Classical and non-classical thyroid hormone intracellular pathways involved in T lymphoma growth
(Bentham Science Publishers, 2015-04)
Thyroid hormones (THs) are important regulators of cell physiology. They are essential for the normal development and growth of mammals, especially for the neural differentiation and the regulation of the metabolism and ...
Target genes of Dpp/BMP signaling pathway revealed by transcriptome profiling in the early D. melanogaster embryo
(Elsevier Science BV., 2016)
In the early Drosophilamelanogaster embryo, the gene regulatory network controlled by Dpp signaling is involved
in the subdivision of dorsal ectoderm into the presumptive dorsal epidermis and amnioserosa. In this work, ...
Circulating MicroRNAs in the Second Trimester From Pregnant Women Who Subsequently Developed Preeclampsia: Potential Candidates as Predictive Biomarkers and Pathway Analysis for Target Genes of miR-204-5p
(2021-09-22)
MicroRNAs (miRNAs) play an important role in the pathophysiology of preeclampsia (PE). However, the expression of circulating miRNAs was not analyzed in the second trimester of pregnancy, a period of major relevance to ...
The MAP Kinases are Differently Utilized by CD28 and CD2 Adhesion Pathways in Superantigen-Activated Jurkat T cells
(Sociedad de Biología de Chile, 2003)
Progesterone receptors:animal models and cell signalling in breast cancer. Diverse activation pathways for the progesterone receptor: possible implications for breast biology and cancer
(Biomed Central, 2002-09-12)
Progesterone and estradiol, and their nuclear receptors, play essential roles in the physiology of the reproductive tract, the mammary gland and the nervous system. Estrogens have traditionally been considered associated ...