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Relationship among oxidative DNA damage, gastric mucosal density and the relevance of cagA, vacA and iceA genotypes of Helicobacter pylori
(Springer, 2008-01-01)
The aim of this study was to evaluate the relationship among oxidative DNA damage, density of Helicobacter pylori and the relevance of cagA, vacA and iceA genotypes of H. pylori. Gastric epithelial cells were isolated from ...
Clinical implication of 14-3-3 epsilon expression in gastric cancer
(BAISHIDENG PUBL GRP CO LTDBEIJING, 2012)
AIM: To evaluate for the first time the protein and mRNA expression of 14-3-3 epsilon in gastric carcinogenesis. METHODS: 14-3-3 epsilon protein expression was determined by western blotting, and mRNA expression was examined ...
Digit ratio (2D:4D) is associated with gastric cancer
(2013-05-01)
Background: Sex steroid exposure during early human development may influence disease susceptibility. Digit ratio (2D:4D) is a putative marker for prenatal hormone exposure and sensitivity, as well as the action of genes ...
Distribution of Open Reading Frames of Plasticity Region of Strain J99 in Helicobacter pylori Strains Isolated from Gastric Carcinoma and Gastritis Patients in Costa Rica
(2000)
The plasticity region of Helicobacter pylori strain J99 is a large chromosomal segment containing 33 strain-specific open reading frames (ORFs) with characteristics of a pathogenicity island. To study the diversity of the ...
Gastric cancer in Chile: A cooperative interhospital study: Ii: Treatment and postoperative evolution
(1975)
The diverse treatment employed in 752 patients with gastric cancer admitted to five hospitals in Chile is presented.Twenty-eight percent of the cases could not be submitted to surgery. Exploratory laparotomy was performed ...
Polymorphisms in RAS/RAF/MEK/ERK pathway are associated with gastric cancer
(MDPI AG, 2019)
The RAS/RAF/MEK/ERK pathway regulates certain cellular functions, including cell proliferation, differentiation, survival, and apoptosis. Dysregulation of this pathway leads to the occurrence and progression of cancers ...
Relevance of the plasminogen activation system in the pathogenesis and progression of gastric cancer
(2018-03)
Gastric cancer is ranked as the third death-causing cancer and one of the most incident malignancies worldwide. Although Helicobacter pylori is the most well-established risk factor for the development of this neoplasm, ...
IL-1ra anti-inflammatory cytokine polymorphism is associated with risk of gastric cancer and chronic gastritis in a Brazilian population, but the TNF-beta pro-inflammatory cytokine is not
(Springer, 2012-07-01)
Genetic polymorphisms in genes that codify inflammatory cytokines have been associated with gastric carcinogenesis. This study evaluated polymorphisms IL-1RN VNTR and TNFB+252A/G in a population from Southeast Brazil with ...