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Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome
(2011)
Background & Aims: Metabolic syndrome is secondary to obesity and characterized by dyslipidemia, insulin resistance, and hypertension. Non-alcoholic fatty liver disease is its hepatic manifestation, whose progression-limiting ...
Activation of skeletal muscle FAPs by LPA requires the Hippo signaling via the FAK pathway
(2023-05)
Lysophosphatidic acid (LPA) is a lysophospholipid that signals through six G-protein coupled receptors (LPARs), LPA1 to LPA6. LPA has been described as a potent modulator of fibrosis in different pathologies. In skeletal ...
A Case of Interstitial Lung Disease With Apical Pleural Thickening: Idiopathic Pleuroparenchymal Fibroelastosis
(Sociedad Española de Neumología y Cirugia Torácica, 2014)
Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a very rare, recently described condition, characterised by fibrotic thickening of the pleural and subpleural parenchyma, predominantly in the upper lobes.1 Clinical ...
A Case of Interstitial Lung Disease With Apical Pleural Thickening: Idiopathic Pleuroparenchymal Fibroelastosis
(Sociedad Española de Neumología y Cirugia Torácica, 2014)
Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a very rare, recently described condition, characterised by fibrotic thickening of the pleural and subpleural parenchyma, predominantly in the upper lobes.1 Clinical ...
Tubulointerstitial injury and proximal tubule albumin transport in early diabetic nephropathy induced by type 1 diabetes mellitus
(Sociedad Latinoamericana de Microscopía Electrónica y Centro Regional de Investigaciones Científicas y Tecnológicas, 2017)
A decrease in the tubular expression of albumin endocytic transporters megalin and cubilin has been
associated with diabetic nephropathy, but there are no comprehensive studies to date relating early tubulointerstitial
injury ...
Inhibition of angiogenesis by platelets in systemic sclerosis patients
(2015)
Abstract
Introduction
Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by microvascular damage, inflammation, and fibrosis. It has become increasingly ...
Pseudotuberculosis ovinaOvine pseudotuberculosis
(Universidad Nacional del Nordeste. Facultad de Ciencias VeterinariasRevista Veterinaria, 2004-03-07)
El objetivo del presente trabajo es informar loshallazgos anatomo e histopatológicos de un rebaño ovino afectado con pseudotuberculosis.Los animales presentaban diarrea, pérdida progresiva de peso, caquexia y muerte. El ...
c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells
(2014)
Abstract
Background
Hard consistency, developed under the influence of tumor cell factors, is a characteristic feature of a breast tumor. Activation of resident fibroblasts ...
The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model
(Oxford University Press, 2018-08)
Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset progressive neurodegenerative disease characterized by upper and lower motoneuron degeneration. A total of 20% of familial ALS (fALS) cases are explained by ...