This article analyzes the results of seven urban sustainability indicators applied at the neighborhood level in the city of Temuco, Chile. The study worked with a selection of indicators taken from the Sustainability Indicators Plan of Vitoria-Gasteiz, Spain, to test their performance and usefulness in an intermediate city and in the Latin American context. For this purpose, a sample of six neighborhoods in Temuco was selected, distinguishing between socioeconomic level and age as independent variables. The comparative results show no significant differences in terms of the socioeconomic level of the neighborhoods, but there is a tendency that the older the neighborhood, the higher the levels of sustainability. © 2022, Universidade do Vale do Rio dos Sinos. All rights reserved.