It is widely known that the abundance and distribution dynamics of populations of small pelagic clupeid fish, such as sardines and anchovies, are affected by large-scale climate variability, which may lead to changeovers to new regimes of small pelagics. However, long-distance climatic oscillations, such as El Niño/La Niña and the Pacific Decadal Oscillation, have been little explored in the Western Mediterranean Sea. We investigated the possible effects of the South Oscillation Index (i.e. the atmospheric oscillation coupled with the El Niño/La Niña) and Pacific Decadal Oscillation on fluctuations in catches of European anchovy (Engraulis encrasicolus) and sardine (Sardina pilchardus) in the Western Mediterranean Sea, and their association with regional climate oscillations (i.e. the Atlantic Multidecadal Oscillation, the North Atlantic Oscillation, the Western Mediterranean Oscillation index, and the Arctic Oscillation). The study covered two periods: (a) landings between 1950 and 2016; and (b) abundance, biomass, and physical condition (i.e., relative condition index) between 2004 and 2016. The main large-scale climatic oscillations in the region were studied using General Additive Models to investigate the relationship between a time series of species measures of European sardine and anchovy from Geographical Subarea 06. Results show that the long-term Pacific Decadal Oscillation favours sardine landings, whereas the combined effect of the Western Mediterranean Oscillation Index and the Atlantic Multidecadal Oscillation favours anchovy. We discuss potential links between the present findings and changes in the plankton community caused by prevailing winds in the region driven by long-distance climate oscillations and their impact on the reduction in small pelagic fish populations in the study area. © 2022 The Author(s)Proyectos de I+D+I, (RETOS-PID2020-118097RB-I00); Ministerio de Ciencia e Innovación, MICINN