artículo
Cocaine-induced vascular damage. Report of one case
Fecha
2012Registro en:
10.4067/S0034-98872012000400013
0034-9887
MEDLINE:22854698
WOS:000304582200013
Autor
Massardo, Teresa
Pino, Angela
Berrocal, Isabel
Castro, Gabriel
Prat, Hernan
Pereira, Jaime
Institución
Resumen
Cocaine abuse is associated with an increased risk of cardiac and cerebro vascular events, such as myocardial infarction, sudden cardiac death, and ischemic stroke. The underlying mechanisms leading to these complications are not fully understood although intravascular thrombus formation and accelerated atherosclerosis are prominent findings. We report a 39-year-old male addicted to cocaine, who presented with three consecutive ischemic events characterized by an acute myocardial infarction and two ischemic strokes complicated by cardiac failure and severe neurological sequelae. The pathophysiology of cocaine-induce vascular damage and the management of the ischemic complications are discussed. (Rev Med Chile 2012; 140: 507-511).